Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

Biomaterials have provided promising strategies towards improving the functions of injured
tissues of the nervous system. Recently, 2D nanomaterials, such as graphene, layered …

Cerium oxide nanoparticles (CNPs) are biocompatible nanozymes exerting multifunctional
biomimetic activities, including superoxide dismutase (SOD), catalase, glutathione …

Cerium oxide nanoparticles (CONPs), owing to their radical scavenging property, have
recently emerged as a therapeutic candidate for oxidative stress-mediated neurological …

Background Alumina nanoparticles (aluminaNPs), which are widely used in a range of daily
and medical fields, have been shown to penetrate blood-brain barrier, and distribute and …

Introduction Axonal transport deficit is a key mechanism involved in neurodegenerative
conditions. Fluoxetine, a commonly used antidepressant for treatment of depression, is …

No medication has been approved for secondary injuries after traumatic brain injury (TBI).
While free radicals are considered a major mediator of secondary injury, conventional …

Neurological disorders such as neurodegenerative diseases and nervous system tumours
affect more than one billion people throughout the globe. The physiological sensitivity of the …

Studies demonstrated that alumina nanoparticles (alumina NPs) impair spatial cognition and
hippocampus-dependent synaptic plasticity. Although alumina NPs accumulate in the …

Sulpiride (SUL), a benzamide derivative, acts as a multitarget drug with extensive biological
properties. However, being a P-glycoprotein efflux substrate with a limited oral bioavailability …