Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …

Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

HIV reverse transcriptase (RT) inhibitors are the important components of highly active
antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in …

The COVID-19 pandemic has evidenced the urgent need for the discovery of broad-
spectrum antiviral therapies that could be deployed in the case of future emergence of novel …

Currently, HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a major
component of the highly active anti-retroviral therapy (HAART) regimen. However, the …

Human immunodeficiency virus (HIV) is the primary infectious agent of acquired
immunodeficiency syndrome (AIDS), and non-nucleoside reverse transcriptase inhibitors …

Human immunodeficiency virus (HIV) is the etiological agent of acquired immunodeficiency
syndrome (AIDS). Nowadays, FDA has approved over thirty antiretroviral drugs grouped in …

The 1918 Spanish influenza pandemic was one of the deadliest infectious disease events in
recorded history, resulting in approximately 50–100 million deaths worldwide. The origins of …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent within the
human population and are characterized by lifelong infections and sporadic recurrences …

More than 40 years into the pandemic, HIV remains a global burden and as of now, there is
no cure in sight. Fortunately, highly active antiretroviral therapy (HAART) has been …