Taurine is one of the most abundant non-essential amino acid in mammals and has many
physiological functions in the nervous, cardiovascular, renal, endocrine, and immune …

DNA sequences with repetitive G-rich structural motifs, which form special structures called
G-quadruplexes, widely exist in the human genome. Here we report the general peroxidase …

Endometriosis is a chronic pleomorphic disorder with pelvic or systemic manifestations, and
is characterized by the presence of endometrial glands and stroma. In the United States, the …

Significance: The incidence of cardiovascular events (CVEs) increases with age,
representing the main cause of death in an elderly population. Aging is associated with …

The lactic acid bacteria (LAB) are essential for food fermentations and their impact on gut
physiology and health is under active exploration. In addition to their well-studied …

Hemolysis, a process by which the destruction of red blood cells leads to the release of
hemoglobin, is a critical event observed during hemolytic disorders. Under oxidative stress …

Historically, the most successful molecular target for antimalarial drugs has been heme
biomineralization within the malarial parasite digestive vacuole. Heme released from …

Extra-intestinal pathogenic Escherichia coli (ExPEC) strains are divided into uropathogenic
E. coli (UPEC), strains causing neonatal meningitis and septicaemic E. coli. The most …

Anthracyclines such as doxorubicin (Dox) are effective chemotherapies, but their use is
limited by cardiac toxicity. We hypothesized that plasma proteomics in women with breast …

A half century ago, Max Perutz and John Kendrew determined the crystal structure of two
heme-containing proteins: hemoglobin and myoglobin, respectively. 1, 2 These landmark …