miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

LJ Galvão-Lima, AHF Morais, RAM Valentim… - Biomedical engineering …, 2021 - Springer
Over the last decades, microRNAs (miRNAs) have emerged as important molecules
associated with the regulation of gene expression in humans and other organisms …

Considerations and suggestions for the reliable analysis of miRNA in plasma using qRT-PCR

E Ban, EJ Song - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) are promising molecules that can regulate gene expression, and their
expression level and type have been associated with early diagnosis, targeted therapy, and …

Quantification of DNA through the NanoDrop spectrophotometer: methodological validation using standard reference material and Sprague Dawley rat and human …

AM García-Alegría, I Anduro-Corona… - … journal of analytical …, 2020 - Wiley Online Library
This study aimed to validate an analytical method to determine DNA concentration using
standard reference material (NIST SRM 2372) and Sprague Dawley rat and human DNA …

Comparison of methods for miRNA isolation and quantification from ovine plasma

K Wright, K de Silva, AC Purdie, KM Plain - Scientific reports, 2020 - nature.com
Abstract microRNA (miRNA) are promising candidates for disease biomarkers as they are
abundant in circulation, highly stable in biological fluids and may yield diagnostic biomarker …

Magnetic nanoparticle-based amplification of microRNA detection in body fluids for early disease diagnosis

I Gessner, JWU Fries, V Brune, S Mathur - Journal of Materials …, 2021 - pubs.rsc.org
Circulating biomarkers such as microRNAs (miRNAs), short noncoding RNA strands,
represent prognostic and diagnostic indicators for a variety of physiological disorders …

The long and short of it: the emerging roles of non-coding RNA in small extracellular vesicles

A Abramowicz, MD Story - Cancers, 2020 - mdpi.com
Small extracellular vesicles (EVs) play a significant role in intercellular communication
through their non-coding RNA (ncRNA) cargo. While the initial examination of EV cargo …

Protocol for serum exosomal miRNAs analysis in prostate cancer patients treated with radiotherapy

B Malla, DM Aebersold, A Dal Pra - Journal of translational medicine, 2018 - Springer
Background Circulating exosomes from prostate cancer (PCa) patients undergoing
radiotherapy are attractive candidate biomarkers for monitoring treatment response. Multiple …

Interference reduction biosensing strategy for highly sensitive microRNA detection

F Chen, G Li, C Wu, L Wang, CN Ko, DL Ma… - Analytical …, 2022 - ACS Publications
MicroRNAs are potential biomarkers for human cancers and other diseases due to their
roles as post-transcriptional regulators for gene expression. However, the detection of …

Circulating microRNAs as biomarkers of gestational diabetes mellitus: updates and perspectives

E Guarino, C Delli Poggi, GE Grieco… - International journal …, 2018 - Wiley Online Library
Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance,
with onset or first recognition during second or third trimester of gestation. It is estimated that …

Circulating microRNAs as reliable tumor biomarkers: Opportunities and Challenges facing Clinical Application

SM El-Daly, SA Gouhar, ZY Abd Elmageed - Journal of Pharmacology and …, 2023 - ASPET
MicroRNAs (miRNAs) are involved in the development of human malignancies, and cells
have the ability to secrete these molecules into extracellular compartments. Thus, cell-free …