Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
W Li, H Ma, J Zhang, L Zhu, C Wang, Y Yang - Scientific reports, 2017 - nature.com
Abstract CD44/CD24 and ALDH1 are widely used cancer stem cell (CSC) markers in breast cancer. However, their expression is not always consistent even in the same subtype of …
Since their identification in 1994, cancer stem cells (CSCs) have been objects of intensive study. Their properties and mechanisms of formation have become a major focus of current …
A Conigliaro, V Costa, A Lo Dico, L Saieva, S Buccheri… - Molecular cancer, 2015 - Springer
Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC), displaying aggressive and metastatic phenotype. Using two different in vitro models, already …
T Yamashita, XW Wang - The Journal of clinical …, 2013 - Am Soc Clin Investig
Liver cancer is an aggressive disease with a poor outcome. Several hepatic stem/progenitor markers are useful for isolating a subset of liver cells with stem cell features, known as …
K Nio, T Yamashita, S Kaneko - Molecular cancer, 2017 - Springer
Liver cancer is an often fatal malignant tumor with a high recurrence rate and chemoresistance. The major malignant phenotypes of cancer, including recurrence …
There is increasing evidence that malignant tumors are initiated and maintained by a sub- population of tumor cells that have similar biological properties to normal adult stem cells …
N Haraguchi, H Ishii, K Mimori… - The Journal of …, 2010 - Am Soc Clin Investig
Cancer stem cells (CSCs) are generally dormant or slowly cycling tumor cells that have the ability to reconstitute tumors. They are thought to be involved in tumor resistance to …
The poor outcome of patients with non-surgically removable advanced hepatocellular carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …