Atrial fibrillation (AF) is the most frequent arrhythmia managed in clinical practice, and it is
linked to an increased risk of death, stroke, and peripheral embolism. The Global Burden of …

Fibrosis is defined as the excessive deposition of extracellular matrix (ECM) proteins in the
interstitium. It is an essential pathological response to chronic inflammation. ECM protein …

This study aimed to investigate the protective effect of angiotensin converting enzyme 2
(ACE2) on lipopolysaccharide (LPS)-induced acute lung injury (ALI). After generating ALI …

In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international
scientific community has joined forces to develop effective treatment strategies. The …

Hypertension, a multifactorial disorder resulting from the interplay between genetic
predisposition and environmental risk factors, affects≈ 30% of adults. Emerging evidence …

Aprominent pathology textbook used in the United States includes an image illustrating the
renal histopathology caused by malignant hypertension. The legend describes striking …

Emerging evidence supports the notion that inflammation fosters the development of
common benign gynecologic disorders, including uterine leiomyoma, endometriosis, and …

From an evolutionary point of view, vitamin D and melatonin appeared very early and share
functions related to defense mechanisms. In the current clinical setting, vitamin D is …

Background Rheumatoid arthritis (RA) is an autoimmune disease of inflammatory joint
damage, wherein C-reactive protein and autoantibodies including rheumatoid factor (RF) …

The increase of Angiontesin-II (Ang-II), one of the key peptides of the renin-angiotensin
system (RAS), and its binding to the Ang-II type 1 receptor (AT1R) during hypertension is a …