SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Abstract The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19
B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
Robust neutralizing antibodies to SARS-CoV-2 infection persist for months
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic with millions infected and more than 1 million fatalities. Questions regarding the …
pandemic with millions infected and more than 1 million fatalities. Questions regarding the …
[HTML][HTML] Case study: prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding was
observed from the upper respiratory tract of a female immunocompromised individual with …
observed from the upper respiratory tract of a female immunocompromised individual with …
Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells
INTRODUCTION Understanding human immune responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) RNA vaccines is of interest for a panoply of reasons …
syndrome coronavirus 2 (SARS-CoV-2) RNA vaccines is of interest for a panoply of reasons …
Virology, transmission, and pathogenesis of SARS-CoV-2
M Cevik, K Kuppalli, J Kindrachuk, M Peiris - bmj, 2020 - bmj.com
• In the respiratory tract, peak SARS-CoV-2 load is observed at the time of symptom onset or
in the first week of illness, with subsequent decline thereafter, indicating the highest …
in the first week of illness, with subsequent decline thereafter, indicating the highest …
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite
Numerous antibodies that neutralize SARS-CoV-2 have been identified, and these generally
target either the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the viral …
target either the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the viral …
[HTML][HTML] SARS-CoV-2 vaccines in development
F Krammer - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late
2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) …
2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) …
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
INTRODUCTION Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients
B Isho, KT Abe, M Zuo, AJ Jamal, B Rathod… - Science …, 2020 - science.org
While the antibody response to SARS-CoV-2 has been extensively studied in blood,
relatively little is known about the antibody response in saliva and its relationship to systemic …
relatively little is known about the antibody response in saliva and its relationship to systemic …