[HTML][HTML] SysPTM: a systematic resource for proteomic research on post-translational modifications

H Li, X Xing, G Ding, Q Li, C Wang, L Xie… - Molecular & Cellular …, 2009 - ASBMB
With the rapid expansion of protein post-translational modification (PTM) research based on
large-scale proteomic work, there is an increasing demand for a suitable repository to …

[HTML][HTML] Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA

E Despras, M Sittewelle, C Pouvelle, N Delrieu… - Nature …, 2016 - nature.com
Translesion polymerase eta (polη) was characterized for its ability to replicate ultraviolet-
induced DNA lesions that stall replicative polymerases, a process promoted by Rad18 …

[HTML][HTML] Multiple post-translational modifications affect heterologous protein synthesis

AA Tokmakov, A Kurotani, T Takagi, M Toyama… - Journal of Biological …, 2012 - ASBMB
Post-translational modifications (PTMs) are required for proper folding of many proteins. The
low capacity for PTMs hinders the production of heterologous proteins in the widely used …

[HTML][HTML] iSuc-PseAAC: predicting lysine succinylation in proteins by incorporating peptide position-specific propensity

Y Xu, YX Ding, J Ding, YH Lei, LY Wu, NY Deng - Scientific reports, 2015 - nature.com
Lysine succinylation in protein is one type of post-translational modifications (PTMs).
Succinylation is associated with some diseases and succinylated sites data just has been …

[HTML][HTML] SUMOylation inhibits FOXM1 activity and delays mitotic transition

SS Myatt, M Kongsema, CWY Man, DJ Kelly… - Oncogene, 2014 - nature.com
The forkhead box transcription factor FOXM1 is an essential effector of G2/M-phase
transition, mitosis and the DNA damage response. As such, it is frequently deregulated …

[HTML][HTML] SUMO-modification of human Nrf2 at K110 and K533 regulates its nucleocytoplasmic localization, stability and transcriptional activity

TS Walters, DJ McIntosh, SM Ingram… - Cellular physiology …, 2021 - ncbi.nlm.nih.gov
Methods: The putative SUMO-binding sites in Nrf2 for human isoform1 (NP_006155. 2) and
mouse homolog (NP_035032. 1) were identified using a computer-based SUMO-predictive …

Improved prediction of lysine acetylation by support vector machines

S Li, H Li, M Li, Y Shyr, L Xie, Y Li - Protein and peptide letters, 2009 - ingentaconnect.com
Reversible acetylation on lysine residues, a crucial post-translational modification (PTM) for
both histone and non-histone proteins, governs many central cellular processes. Due to …

Sumoylation of Arabidopsis heat shock factor A2 (HsfA2) modifies its activity during acquired thermotholerance

R Cohen-Peer, S Schuster, D Meiri, A Breiman… - Plant molecular …, 2010 - Springer
Post-translational modification of target proteins by the small ubiquitin-like modifier protein
(SUMO) regulate many cellular processes. In this work we show SUMOylation of the heat …

[HTML][HTML] Comprehensive analysis of regulation of DNA methyltransferase isoforms in human breast tumors

M Hegde, MB Joshi - Journal of Cancer Research and Clinical Oncology, 2021 - Springer
Significant reprogramming of epigenome is widely described during pathogenesis of breast
cancer. Transformation of normal cell to hyperplastic cell and to neoplastic phenotype is …

[HTML][HTML] Mutation-structure-function relationship based integrated strategy reveals the potential impact of deleterious missense mutations in autophagy related proteins …

FM Awan, A Obaid, A Ikram, HA Janjua - International journal of molecular …, 2017 - mdpi.com
Autophagy, an evolutionary conserved multifaceted lysosome-mediated bulk degradation
system, plays a vital role in liver pathologies including hepatocellular carcinoma (HCC). Post …