Mesenchymal stem cells and their derived exosomes to combat Covid–19

M Yousefi Dehbidi, N Goodarzi… - Reviews in Medical …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is causing an ongoing
pandemic of coronavirus disease 2019 (Covid‐19). Effective therapies are required for the …

Systematic review and meta-analysis of cell therapy for COVID-19: global clinical trial landscape, published safety/efficacy outcomes, cell product manufacturing and …

PS Couto, N Al-Arawe, IS Filgueiras… - Frontiers in …, 2023 - frontiersin.org
During the pandemic of severe respiratory distress syndrome coronavirus 2 (SARS-CoV2),
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …

Safety of DW-MSC infusion in patients with low clinical risk COVID-19 infection: a randomized, double-blind, placebo-controlled trial

M Karyana, I Djaharuddin, L Rif'ati, M Arif… - Stem cell research & …, 2022 - Springer
Background Due to their immunomodulatory properties, mesenchymal stem cells (MSCs)
have been proposed to have therapeutic potential to improve clinical outcomes in COVID …

Therapeutic role of mesenchymal stem cell-derived exosomes in respiratory disease

MJ Zargar, S Kaviani, M Vasei… - Stem Cell Research & …, 2022 - Springer
Exosomes are extracellular vesicles found in various tissues, blood circulation, and tissue
fluids, secreted into the extracellular environment by fusing a multivesicular body with a …

Molecular insight into the therapeutic effects of stem cell-derived exosomes in respiratory diseases and the potential for pulmonary delivery

MH Azhdari, N Goodarzi, M Doroudian… - International Journal of …, 2022 - mdpi.com
Respiratory diseases are the cause of millions of deaths annually around the world. Despite
the recent growth of our understanding of underlying mechanisms contributing to the …

Mesenchymal stem/stromal cell therapy for COVID-19 pneumonia: potential mechanisms, current clinical evidence, and future perspectives

W Yao, L Shi, Y Zhang, H Dong, Y Zhang - Stem Cell Research & Therapy, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread into more than 200 countries …

Efficacy of MSC in patients with severe COVID-19: analysis of the literature and a case study

M Grumet, J Sherman, BS Dorf - Stem cells translational …, 2022 - academic.oup.com
Patients with severe COVID-19 experience cytokine storm, an uncontrolled upregulation of
pro-inflammatory cytokines, which if unresolved leads to acute respiratory distress syndrome …

Cell therapy in patients with COVID-19 using Wharton's jelly mesenchymal stem cells: a phase 1 clinical trial

M Saleh, AA Vaezi, R Aliannejad… - Stem cell research & …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have received particular attention
because of their ability to modulate the immune system and inhibit inflammation caused by …

Umbilical cord blood transplantation: connecting its origin to its future

G Sanchez-Petitto, K Rezvani, M Daher… - Stem cells …, 2023 - academic.oup.com
Transplantation of umbilical cord blood (UCB) is an attractive alternative source of
hematopoietic stem cells (HSCs). The unique properties of cord blood and its distinct …

[HTML][HTML] Anti‐SARS‐CoV‐2 effect of extracellular vesicles released from mesenchymal stem cells

S Chutipongtanate, S Kongsomros… - Journal of …, 2022 - ncbi.nlm.nih.gov
As of 10 December 2021, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2
accounted for 267 million people with up to 5.3 million deaths worldwide (https://covid19 …