Mesenchymal stem cell therapy for COVID-19 infection

SMM Alavi-Dana, Y Gholami, M Meghdadi… - …, 2024 - Springer
COVID-19 emerged in December 2019 in Wuhan, China, spread worldwide rapidly, and
caused millions of deaths in a short time. Many preclinical and clinical studies were …

Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles in COVID-19-induced ARDS: Mechanisms of action, research progress, challenges …

S Moradinasab, A Pourbagheri-Sigaroodi… - International …, 2021 - Elsevier
In late 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan city, Hubei province,
China. Rapidly escalated into a worldwide pandemic, it has caused an unprecedented and …

Clinical efficacy and mechanism of mesenchymal stromal cells in treatment of COVID-19

K Lu, S Geng, S Tang, H Yang, W Xiong, F Xu… - Stem cell research & …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a highly infectious epidemic disease that
has seriously affected human health worldwide. To date, however, there is still no definitive …

Facing the challenges in the COVID-19 pandemic era: from standard treatments to the umbilical cord-derived mesenchymal stromal cells as a new therapeutic strategy

E Russo, S Corrao, F Di Gaudio, G Alberti, M Caprnda… - Cells, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which counts more than 650 million cases and …

Exosomes in COVID‐19 infection: Focus on role in diagnosis, pathogenesis, immunity, and clinical trials

A Aljuhani, O Albalawi, R Albalawi… - Cell Biology …, 2023 - Wiley Online Library
Since the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
spread as a new strain of coronavirus disease (COVID‐19) and progressed as a global …

Mesenchymal stem cell-derived exosomal miR-146a reverses diabetic β-cell dedifferentiation

Q He, J Song, C Cui, J Wang, H Hu, X Guo… - Stem Cell Research & …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) show promising therapeutic potential
in treating type 2 diabetes mellitus (T2DM) in clinical studies. Accumulating evidence has …

Direct, indirect, post-infection damages induced by coronavirus in the human body: an overview

SP Priya, PM Sunil, S Varma, C Brigi, MFAR Isnadi… - Virusdisease, 2022 - Springer
Background Severe acute respiratory syndrome Coronavirus-2 invades the cells via ACE2
receptor and damages multiple organs of the human body. Understanding the pathological …

[HTML][HTML] Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies

NK Farkhad, H Reihani, AA Moghadam… - Regenerative …, 2021 - Elsevier
The Covid-19 disease has recently become one of the biggest challenges globally, and
there is still no specific medication. Findings showed the immune system in severe Covid-19 …

Is there a place for mesenchymal stromal cell-based therapies in the therapeutic armamentarium against COVID-19?

KN da Silva, ALN Gobatto, ZSM Costa-Ferro… - Stem cell research & …, 2021 - Springer
The COVID-19 pandemic, caused by the rapid global spread of the novel coronavirus
(SARS-CoV-2), has caused healthcare systems to collapse and led to hundreds of …

Immunopathology and immunosenescence, the immunological key words of severe COVID-19. Is there a role for stem cell transplantation?

ME Ligotti, F Pojero, G Accardi, A Aiello… - Frontiers in Cell and …, 2021 - frontiersin.org
The outcomes of Coronavirus disease-2019 (COVID-19) vary depending on the age, health
status and sex of an individual, ranging from asymptomatic to lethal. From an immunologic …