Exosomes based strategies for cardiovascular diseases: Opportunities and challenges

H Li, J Zhang, M Tan, Y Yin, Y Song, Y Zhao, L Yan… - Biomaterials, 2024 - Elsevier
Exosomes, as nanoscale extracellular vesicles (EVs), are secreted by all types of cells to
facilitate intercellular communication in living organisms. After being taken up by …

Tissue repair strategies: What we have learned from COVID-19 in the application of MSCs therapy

YE Li, A Ajoolabady, M Dhanasekaran, J Ren - Pharmacological Research, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) infection evokes severe proinflammatory
storm and pulmonary infection with the number of confirmed cases (more than 200 million) …

Advances in Biomarkers for Diagnosis and Treatment of ARDS

R Ge, F Wang, Z Peng - Diagnostics, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a common and fatal disease, characterized
by lung inflammation, edema, poor oxygenation, and the need for mechanical ventilation, or …

Molecular mechanisms responsible for mesenchymal stem cell-based treatment of viral diseases

CR Harrell, B Popovska Jovicic, V Djonov, V Volarevic - Pathogens, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are adult, immunomodulatory stem cells which reside in
almost all postnatal tissues. Viral antigens and damage-associated molecular patterns …

Mesenchymal stem cell treatment for hyperactive immune response in patients with COVID-19

R Manoharan, RA Kore, JL Mehta - Immunotherapy, 2022 - Taylor & Francis
The human immune system protects the body against invasive organisms and kicks into a
hyperactive mode in COVID-19 patients, particularly in those who are critically sick …

One-year follow-up study after patients with severe COVID-19 received human umbilical cord mesenchymal stem cells treatment

L Shi, Y Zheng, Z Cheng, N Ji, C Niu, Y Wang… - Stem Cell Research & …, 2022 - Springer
Background The novel coronavirus is still mutating, and the pandemic continues.
Meanwhile, many COVID-19 survivors have residual postinfection clinical manifestations …

Treatment of acute respiratory distress syndrome caused by COVID-19 with human umbilical cord mesenchymal stem cells

T Bukreieva, H Svitina, V Nikulina, A Vega… - International Journal of …, 2023 - mdpi.com
This study aimed to identify the impact of mesenchymal stem cell transplantation on the
safety and clinical outcomes of patients with severe COVID-19. This research focused on …

Stem cell therapy: a novel approach against emerging and re-emerging viral infections with special reference to SARS-CoV-2

V Khandelwal, T Sharma, S Gupta, S Singh… - Molecular biology …, 2023 - Springer
The past several decades have witnessed the emergence and re-emergence of many
infectious viral agents, flaviviruses, influenza, filoviruses, alphaviruses, and coronaviruses …

Recommendation: Treatment of clinical long COVID encephalopathies with nasal administered mesenchymal stromal cell extracellular vesicles

PW Askenase - Frontiers in Nanotechnology, 2022 - frontiersin.org
We propose therapy with extracellular vesicles (EVs) for dominant central nervous system
aspects of chronic Long COVID Syndromes (LCS). These clinical conditions have a delayed …

Rationale for combined therapies in severe-to-critical COVID-19 patients

A Gonzaga, E Andreu, LM Hernandez-Blasco… - Frontiers in …, 2023 - frontiersin.org
An unprecedented global social and economic impact as well as a significant number of
fatalities have been brought on by the coronavirus disease 2019 (COVID-19), produced by …