Decellularized extracellular matrix for remodeling bioengineering organoid's microenvironment

L Zhu, J Yuhan, H Yu, B Zhang, K Huang, L Zhu - Small, 2023 - Wiley Online Library
Over the past decade, stem cell‐and tumor‐derived organoids are the most promising
models in developmental biology and disease modeling, respectively. The matrix is one of …

[HTML][HTML] Sterilization and disinfection methods for decellularized matrix materials: Review, consideration and proposal

M Tao, T Ao, X Mao, X Yan, R Javed, W Hou, Y Wang… - Bioactive materials, 2021 - Elsevier
Sterilization is the process of killing all microorganisms, while disinfection is the process of
killing or removing all kinds of pathogenic microorganisms except bacterial spores …

Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation

G Mazza, K Rombouts, A Rennie Hall, L Urbani… - Scientific reports, 2015 - nature.com
Liver synthetic and metabolic function can only be optimised by the growth of cells within a
supportive liver matrix. This can be achieved by the utilisation of decellularised human liver …

A review of cellularization strategies for tissue engineering of whole organs

ME Scarritt, NC Pashos, BA Bunnell - Frontiers in bioengineering and …, 2015 - frontiersin.org
With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

Strategies based on organ decellularization and recellularization

KH Hillebrandt, H Everwien, N Haep… - Transplant …, 2019 - Wiley Online Library
Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Biocompatibility evaluation of tissue-engineered decellularized scaffolds for biomedical application

KH Hussein, KM Park, KS Kang, HM Woo - Materials Science and …, 2016 - Elsevier
Biomaterials based on seeding of cells on decellularized scaffolds have gained increasing
interest in the last few years and suggested to serve as an alternative approach to …

[HTML][HTML] Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: What does the future have in store for us?

B Lascaris, VE de Meijer, RJ Porte - Journal of Hepatology, 2022 - Elsevier
Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

The host response to naturally-derived extracellular matrix biomaterials

AH Morris, DK Stamer, TR Kyriakides - Seminars in immunology, 2017 - Elsevier
Biomaterials based on natural materials including decellularized tissues and tissue-derived
hydrogels are becoming more widely used for clinical applications. Because of their native …

[HTML][HTML] Decellularized xenogeneic scaffolds in transplantation and tissue engineering: Immunogenicity versus positive cell stimulation

MS Massaro, R Palek, J Rosendorf… - Materials Science and …, 2021 - Elsevier
Seriously compromised function of some organs can only be restored by transplantation.
Due to the shortage of human donors, the need to find another source of organs is of primary …

[HTML][HTML] Extracellular matrix scaffold-immune microenvironment modulates tissue regeneration

Y Yu, W Zhang, X Liu, H Wang, J Shen, H Xiao… - Composites Part B …, 2022 - Elsevier
A promising paradigm to regenerative medicine involves the application of biomaterials,
which makes a spurt of progress in the past 20 years. Of various biomaterials, decellularized …