[HTML][HTML] The temporal hyper-morbidity of asthma and attention deficit disorder: implications for interpretation based on comparison of prospective and cross-sectional …

PH Chai, S Chang, D Cawthorpe - Psychiatry investigation, 2021 - ncbi.nlm.nih.gov
Objective The purpose of this study was to test the hypothesis that a significant temporal
relationship exists between asthma and attention deficit hyperactivity disorder (ADHD) …

[HTML][HTML] Behavioural side effects of inhaled corticosteroids among children and adolescents with asthma

KS Bodum, BE Hjerrild, S Dalsgaard, SLM Rubak - Respiratory Research, 2022 - Springer
Background Inhalation corticosteroids (ICS) are prescribed for treatment of asthma in
approximately 3% of all children in Denmark. Despite limited evidence, case reports suggest …

[HTML][HTML] JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice

R Pandey, M Bakay, BP Strenkowski, HS Hain… - Scientific Reports, 2021 - nature.com
CLEC16A is implicated in multiple autoimmune diseases. We generated an inducible whole-
body knockout (KO), Clec16a ΔUBC mice to address the role of CLEC16A loss of function …

Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis

T Wang, W Sun, H Wu, Y Cheng, Y Li… - Occupational and …, 2021 - oem.bmj.com
Objectives Susceptibility loci of idiopathic pulmonary fibrosis and chronic obstructive
pulmonary disease were also significantly associated with the predisposition of coal …

[HTML][HTML] Relationship of soluble interleukin-6 receptors with asthma: a Mendelian randomization study

Y Raita, Z Zhu, CA Camargo Jr, RJ Freishtat… - Frontiers in …, 2021 - frontiersin.org
Purpose: Emerging evidence suggests a potential role of interleukin-6 pathways—trans-
signaling with soluble interleukin-6 receptors—in the asthma pathobiology. Despite the …

Interplay of ADHD polygenic liability with birth-related, somatic, and psychosocial factors in ADHD: a nationwide study

I Brikell, T Wimberley, C Albiñana… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Attention deficit hyperactivity disorder (ADHD) is a multifactorial
neurodevelopmental disorder, yet the interplay between ADHD polygenic risk scores (PRSs) …

Early-life airway microbiome and childhood asthma development

Z Zhu - European Respiratory Journal, 2024 - Eur Respiratory Soc
Extract Asthma is the most common chronic respiratory disease among children, with
approximately 10–15% of children affected in the world [1]. Epidemiological research has …

Mendelian randomisation studies of attention deficit hyperactivity disorder

L Riglin, E Stergiakouli - JCPP advances, 2022 - Wiley Online Library
Background Observational studies have found Attention Deficit Hyperactivity Disorder
(ADHD) to be associated with an increased risk of adverse outcomes as well as with early …

Using human genetics to understand the phenotypic association between chronotype and breast cancer

X Wu, C Yang, Y Zou, SE Jones, X Zhao… - Journal of Sleep …, 2023 - Wiley Online Library
Little is known regarding the shared genetic influences underlying the observed phenotypic
association between chronotype and breast cancer in women. Leveraging summary …

Associations of combined phenotypic ageing and genetic risk with incidence of chronic respiratory diseases in the UK Biobank: a prospective cohort study

T Wang, W Duan, X Jia, X Huang, Y Liu… - European …, 2024 - Eur Respiratory Soc
Background Accelerated biological ageing has been associated with an increased risk of
several chronic respiratory diseases. However, the associations between phenotypic age, a …