Phytic acid and its interactions in food components, health benefits, and applications: A comprehensive review

W Chen, D Xu - Trends in Food Science & Technology, 2023 - Elsevier
Background The development of the future food industry is heavily focused on plant-based
foods. These foods usually contain phytic acid (PA), which has been considered an anti …

Advances and perspectives in fluorescent probes for imaging hepatopathy-related biomarkers

W Quan, W Song, Q Zhang, H Huang, W Lin - Coordination Chemistry …, 2023 - Elsevier
As the metabolic and detoxification center of the body, the liver is closely involved in many
critical physiological processes, such as metabolism, immunity, digestion, storage of liver …

X‐ray‐Induced release of nitric oxide from hafnium‐based nanoradiosensitizers for enhanced radio‐immunotherapy

N Liu, J Zhu, W Zhu, L Chen, M Li, J Shen… - Advanced …, 2023 - Wiley Online Library
Radiotherapy (RT) is an extensively used strategy for cancer treatment, but its therapeutic
effect is usually limited by the abnormal tumor microenvironment (TME) and it lacks the …

Continuous spatiotemporal therapy of a full-API nanodrug via multi-step tandem endogenous biosynthesis

F Fang, S Wang, Y Song, M Sun, WC Chen… - Nature …, 2023 - nature.com
Nanomedicine holds great promise to enhance cancer therapy. However, low active
pharmaceutical ingredient (API) loading content, unpredictable drug release, and potential …

Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis, in vitro biological evaluation, and in silico ADMET analysis with …

AS Hassan, NM Morsy, WM Aboulthana, A Ragab - RSC advances, 2023 - pubs.rsc.org
Recently, scientists developed a powerful strategy called “one drug-multiple targets” to
discover vital and unique therapies to fight the most challenging diseases. Novel derivatives …

Rational design of molecular phototheranostic platform for NIR-II fluorescence imaging guided chemodynamic-photothermal combined therapy

G Wu, B Sun, Y He, X Tan, Q Pan, S Yang, N Li… - Chemical Engineering …, 2023 - Elsevier
The strategy of synergetic chemodynamic treatment (CDT) and photothermal therapy (PTT)
to improve the anticancer effect has been a hot spot in the field of biomedicine. Herein, a …

2D Nano‐Sonosensitizers Facilitate Energy Transfer to Enhance Sonodynamic Therapy

G Lin, GT Nash, T Luo, I Ghosh, S Sohoni… - Advanced …, 2023 - Wiley Online Library
Although sonodynamic therapy (SDT) has shown promise for cancer treatment, the lack of
efficient sonosensitizers (SSs) has limited the clinical application of SDT. Here, a new …

Steerable microneedles enabling deep delivery of photosensitizers and CRISPR/Cas9 systems for effective combination cancer therapy

T Wang, G Chen, S Zhang, D Li, G Wei, X Zhao… - Nano Letters, 2023 - ACS Publications
Although gene therapy has shown prospects in treating triple-negative breast cancer, it is
insufficient to treat such a malignant tumor. Herein, nanoparticles (NPs)-embedded …

Beyond extracellular vesicles: hybrid membrane nanovesicles as emerging advanced tools for biomedical applications

M Sun, J Yang, Y Fan, Y Zhang, J Sun, M Hu… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs), involved in essential physiological and pathological processes
of the organism, have emerged as powerful tools for disease treatment owing to their unique …

Synthesis, spectroscopic, thermal analysis and in vitro cytotoxicity, anticholinesterase and antioxidant activities of new Co (II), Ni (II), Cu (II), Zn (II), and Ru (III) …

R Çakmak, B Ay, E Çınar, E Başaran, S Akkoç… - Journal of Molecular …, 2023 - Elsevier
Metal-based drugs have gained significant importance in medicine in recent years. In this
research, a series of new Co (II), Ni (II), Cu (II), Zn (II), and Ru (III) complexes of a Schiff base …