The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …

The role of the nuclear hormone receptor peroxisome proliferator-activated receptor β/δ
(PPARβ/δ) in carcinogenesis is controversial because conflicting studies indicate that it both …

Oxidative stress has been found to be associated with the progression of neurodegenerative
diseases such as Alzheimer's, Parkinson's, Lou Gehrig's, etc. In the recent years, cerium …

Retinoic acid (RA) regulates gene transcription by activating the nuclear receptors retinoic
acid receptor (RAR) and peroxisome proliferator-activated receptor (PPAR) β/δ and their …

In this review study, we focus on potential benefits of the transcription factor PPARδ and its
ligand erucic acid (EA) in management of neuroectodermal tumors and Parkinson's …

Peroxisome proliferator-activated receptors (PPARα,-β/δ and-γ) are lipid-activated
transcription factors. Synthetic PPARα and PPARγ ligands have neuroprotective properties …

The proliferation, differentiation, and migration of neural precursor cells occur not only
during embryonic development but also within distinct regions of the adult brain through the …

Astrocytes are the gatekeepers of neuronal energy supply. In neurodegenerative diseases,
bioenergetics demand increases and becomes reliant upon fatty acid oxidation as a source …

Multiple sclerosis is a complex neurodegenerative disease, thought to arise through
autoimmunity against antigens of the central nervous system. The autoimmunity hypothesis …

Nuclear receptors (NRs) are responsible for the regulation of diverse developmental and
physiological systems in metazoans. NR actions can be the result of genomic and non …