Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Central nervous system (CNS) diseases are one of the major health problems. However,
blood-brain barrier (BBB) makes traditional oral and intravenous delivery of CNS drugs …

Introduction This work aimed to develop chitosan-coated cubosomal nanoparticles intended
for nose-to-brain delivery of paliperidone palmitate. They were compared with standard and …

The nasopharynx, at the back of the nose, constitutes the dominant initial viral infection
trigger zone along the upper respiratory tract. However, as per the standard recommended …

The surge in neurological disorders necessitates innovative strategies for delivering active
pharmaceutical ingredients to the brain. The non-invasive intranasal route has emerged as …

Delivering vaccines to the posterior nose has been proposed to induce mucosal
immunization. However, conventional nasal devices often fail to deliver sufficient doses to …

Chronic and allergic rhinosinusitis impacts approximately 12% of the global population.
Challenges in rhinosinusitis treatment include paranasal sinus inaccessibility and variability …

3D printing has emerged as a groundbreaking technology with transformative applications
in various health care domains. In drug delivery, it enables the precise fabrication of …

Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …

Although nasal inhalation products are becoming more and more important for the delivery
of medicines, characterization of these products for quality control and assessment of …