COVID-19 therapeutics

D Focosi, M Franchini, F Maggi… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Since the emergence of COVID-19 in 2020, an unprecedented range of therapeutic options
has been studied and deployed. Healthcare providers have multiple treatment approaches …

Emerging anti-spike monoclonal antibodies against SARS-CoV-2

EE Ordaya, RR Razonable - Expert Opinion on Biological Therapy, 2024 - Taylor & Francis
Introduction Anti-spike monoclonal antibodies (mAbs) were previously authorized for the
prevention and treatment of COVID-19 in immunocompromised patients. However, they are …

Carbonized aerogel/ZnO-based dispersive solid phase extraction of daclatasvir and sofosbuvir from biological samples prior to liquid chromatography–tandem mass …

EM Khosrowshahi, RH Sabet, MRA Mogaddam… - … of Pharmaceutical and …, 2024 - Elsevier
Daclatasvir and sofosbuvir are antiviral medications utilized in the treatment of chronic
hepatitis C virus (HCV) infection. Due to their low therapeutic index, careful monitoring is …

Treatment of chronic COVID‐19 with convalescent/postvaccination plasma in patients with hematologic malignancies

M Janssen, A Leo, C Wolf, M Stenzinger… - … Journal of Cancer, 2024 - Wiley Online Library
Immunocompromised patients are at high risk to fail clearance of SARS‐CoV‐2. Prolonged
COVID‐19 constitutes a health risk and a management problem as cancer treatments often …

Passive immunotherapies for the next influenza pandemic

D Focosi, M Franchini, JW Senefeld… - Reviews in Medical …, 2024 - Wiley Online Library
Influenzavirus is among the most relevant candidates for a next pandemic. We review here
the phylogeny of former influenza pandemics, and discuss candidate lineages. After briefly …

The Role of Convalescent Plasma in COVID-19: A Conclusive Post-Pandemic Review

M Franchini, D Focosi - Life, 2023 - mdpi.com
COVID-19 convalescent plasma (CCP) has represented the frontline response to the COVID-
19 pandemic, largely because of encouraging historical evidences in previous pandemics …

Early combination of sotrovimab with nirmatrelvir/ritonavir or remdesivir is associated with low rate of persisting SARS CoV-2 infection in immunocompromised …

I Gentile, G Viceconte, F Cuccurullo, D Pietroluongo… - medRxiv, 2024 - medrxiv.org
Background Immunocompromised patients are at high risk of developing
persisting/prolonged COVID-19. Data concerning early combined use of antivirals and …