Role of E3 ubiquitin ligases and deubiquitinating enzymes in SARS-CoV-2 infection

M Zhao, M Zhang, Z Yang, Z Zhou, J Huang… - Frontiers in Cellular …, 2023 - frontiersin.org
Ever since its emergence in 2019, COVID-19 has rapidly disseminated worldwide,
engendering a pervasive pandemic that has profoundly impacted healthcare systems and …

Integration of Omics Data and Network Models to Unveil Negative Aspects of SARS-CoV-2, from Pathogenic Mechanisms to Drug Repurposing

L Bernardo, A Lomagno, PL Mauri, D Di Silvestre - Biology, 2023 - mdpi.com
Simple Summary SARS-CoV-2 caused the COVID-19 health emergency, affecting millions
of people worldwide. Samples collected from hospitalized or dead patients from the early …

Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug …

MP Mosharaf, MS Reza, MK Kibria, FF Ahmed… - Scientific reports, 2022 - nature.com
The pandemic threat of COVID-19 has severely destroyed human life as well as the
economy around the world. Although, the vaccination has reduced the outspread, but …

Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated …

FF Ahmed, MS Reza, MS Sarker, MS Islam… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe
global pandemic due to its high pathogenicity and death rate starting from the end of 2019 …

Structure-based virtual screening reveals ibrutinib and zanubrutinib as potential repurposed drugs against COVID-19

S Kaliamurthi, G Selvaraj, C Selvaraj, SK Singh… - International Journal of …, 2021 - mdpi.com
Coronavirus disease (COVID)-19 is the leading global health threat to date caused by a
severe acute respiratory syndrome coronavirus (SARS-CoV-2). Recent clinical trials …

Meta-data analysis to explore the hub of the hub-genes that influence SARS-CoV-2 infections highlighting their pathogenetic processes and drugs repurposing

MP Mosharaf, MK Kibria, MB Hossen, MA Islam… - Vaccines, 2022 - mdpi.com
The pandemic of SARS-CoV-2 infections is a severe threat to human life and the world
economic condition. Although vaccination has reduced the outspread, but still the situation is …

Identification of host genomic biomarkers from multiple transcriptomics datasets for diagnosis and therapies of SARS-CoV-2 infections

B Sarker, MM Rahaman, MA Islam, MH Alamin… - Plos one, 2023 - journals.plos.org
The pandemic of COVID-19 is a severe threat to human life and the global economy.
Despite the success of vaccination efforts in reducing the spread of the virus, the situation …

Bioinformatics approach to identify the hub gene associated with COVID‐19 and idiopathic pulmonary fibrosis

W Shi, T Li, H Li, J Ren, M Lv, Q Wang, Y He… - IET Systems …, 2023 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) has developed into a global health
crisis. Pulmonary fibrosis, as one of the complications of SARS‐CoV‐2 infection, deserves …

The effect of various compounds on the COVID mechanisms, from chemical to molecular aspects

S Mahmoudi, MM Dehkordi, MH Asgarshamsi - Biophysical Chemistry, 2022 - Elsevier
The novel coronavirus that caused COVID-19 pandemic is SARS-CoV-2. Although various
vaccines are currently being used to prevent the disease's severe consequences, there is …

Prospects of novel and repurposed immunomodulatory drugs against acute respiratory distress syndrome (ARDS) associated with covid-19 disease

SS Nayak, A Naidu, SL Sudhakaran, S Vino… - Journal of personalized …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is intricately linked with SARS-CoV-2-
associated disease severity and mortality, especially in patients with co-morbidities. Lung …