Probiotics, prebiotics and synbiotics: Safe options for next-generation therapeutics

MK Yadav, I Kumari, B Singh, KK Sharma… - Applied microbiology and …, 2022 - Springer
Probiotics have been considered as an economical and safe alternative for the treatment of
a large number of chronic diseases and improvement of human health. They are known to …

Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy

A Basu, G Ramamoorthi, G Albert, C Gallen… - Frontiers in …, 2021 - frontiersin.org
Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells
in the tumor which are critical for activation of anti-tumor response either directly by …

Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

PLGA-based nanoparticles: an overview of biomedical applications

F Danhier, E Ansorena, JM Silva, R Coco… - Journal of controlled …, 2012 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

The influence of nutritional factors on immunological outcomes

E Tourkochristou, C Triantos, A Mouzaki - Frontiers in immunology, 2021 - frontiersin.org
Through food intake, humans obtain a variety of nutrients that are essential for growth,
cellular function, tissue development, energy, and immune defense. A special interaction …

Molecular targets for biological therapies of severe asthma

C Pelaia, C Crimi, A Vatrella, C Tinello… - Frontiers in …, 2020 - frontiersin.org
Asthma is a heterogeneous respiratory disease characterized by usually reversible
bronchial obstruction, which is clinically expressed by different phenotypes driven by …

Cellular mechanisms underlying eosinophilic and neutrophilic airway inflammation in asthma

G Pelaia, A Vatrella, MT Busceti, L Gallelli… - Mediators of …, 2015 - Wiley Online Library
Asthma is a phenotypically heterogeneous chronic disease of the airways, characterized by
either predominant eosinophilic or neutrophilic, or even mixed eosinophilic/neutrophilic …

Immune system targeting by biodegradable nanoparticles for cancer vaccines

JM Silva, M Videira, R Gaspar, V Préat… - Journal of controlled …, 2013 - Elsevier
The concept of therapeutic cancer vaccines is based on the activation of the immune system
against tumor cells after the presentation of tumor antigens. Nanoparticles (NPs) have …

Dendritic cells a critical link to alveolar bone loss and systemic disease risk in periodontitis: Immunotherapeutic implications

AR El‐Awady, M Elashiry, AC Morandini… - Periodontology …, 2022 - Wiley Online Library
Extensive research in humans and animal models has begun to unravel the complex
mechanisms that drive the immunopathogenesis of periodontitis. Neutrophils mount an early …

The role of regulatory T cells in multiple sclerosis

AL Zozulya, H Wiendl - Nature clinical practice Neurology, 2008 - nature.com
The dysregulation of inflammatory responses and of immune self-tolerance is considered to
be a key element in the autoreactive immune response in multiple sclerosis (MS) …