An overview of repurposed drugs for potential COVID-19 treatment

K Govender, A Chuturgoon - Antibiotics, 2022 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has placed severe constraints on
healthcare systems around the globe. The SARS-CoV-2 virus has caused upheaval in the …

A clinical update on SARS-CoV-2: Pathology and development of potential inhibitors

DD Singh, I Han, EH Choi, DK Yadav - Current Issues in Molecular …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome) is highly infectious and causes severe
acute respiratory distress syndrome (SARD), immune suppression, and multi-organ failure …

In vitro and in vivo suppression of SARS‐CoV‐2 replication by a modified, short, cell‐penetrating peptide targeting the C‐terminal domain of the viral spike protein

D Kim, J Kim, S An, M Kim, K Baek… - Journal of Medical …, 2023 - Wiley Online Library
Peptides are promising therapeutic agents for COVID‐19 because of their specificity, easy
synthesis, and ability to be fine‐tuned. We previously demonstrated that a cell‐permeable …

Timeline of SARS-CoV-2 transmission in Sabah, Malaysia: Tracking the molecular evolution

KN Balakrishnan, CW Yew, ETJ Chong, S Daim… - Pathogens, 2023 - mdpi.com
Background: The COVID-19 pandemic poses an unprecedented public health challenge in
Malaysia. The impact of COVID-19 varies between countries, including geographically …

An approach for engineering peptides for competitive inhibition of the sars-cov-2 spike protein

AP de Abreu, FC Carvalho, D Mariano, LL Bastos… - Molecules, 2024 - mdpi.com
SARS-CoV-2 is the virus responsible for a respiratory disease called COVID-19 that
devastated global public health. Since 2020, there has been an intense effort by the …

An In Silico Design of Peptides Targeting the S1/S2 Cleavage Site of the SARS-CoV-2 Spike Protein

C Ho, WFWM Nazarie, PC Lee - Viruses, 2023 - mdpi.com
SARS-CoV-2, responsible for the COVID-19 pandemic, invades host cells via its spike
protein, which includes critical binding regions, such as the receptor-binding domain (RBD) …

Oral intake of heat-killed Lactiplantibacillus pentosus ONRICb0240 partially protects mice against SARS-CoV-2 infection

M Kiso, R Uraki, M Ito, S Yamayoshi, Y Kotani… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
ongoing coronavirus pandemic. Besides vaccines and antiviral drugs, probiotics have …

Analysis of Differentially Expressed circRNAs and mRNAs and Their Correlation Network in Peripheral Blood of COVID-19 Patients

Y Liu, Y Wang, Y Bai - 2023 7th International Conference on …, 2023 - ieeexplore.ieee.org
Since the global outbreak of SARS-CoV-2 in 2019, numerous studies have been conducted
on the characterization, infection and treatment of COVID-19 virus. In recent years …