Multi-scale and integrative modelling approaches

G Bocharov, V Volpert, B Ludewig… - … Immunology of Virus …, 2018 - Springer
The term multi-scale models is used with different meanings in different sciences. In
mathematics, it implies the presence of one or several small parameters, homogenization …

[HTML][HTML] Гематологические особенности при токсических гепатитах

ББ Хасанов - Достижения науки и образования, 2022 - cyberleninka.ru
в работе представлен краткий обзор последних клинических и экспериментальных
данных о влиянии гепатитов и циррозов печени на гематологические показатели …

A method for source–depth estimation using a Hybrid Optical/Gamma Camera

NSD Dawood - 2019 - figshare.le.ac.uk
This work describes a new imaging technique to estimate the depth of radionuclide
accumulations in relation to patient anatomy using a novel small field of view (SFOV) hybrid …

Detecting and quantifying cryptic HIV replication

R Zurakowski - US Patent 9,874,563, 2018 - Google Patents
The present invention relates to a novel method for detecting efficient cryptic HIV replication
in a patient who receives a suppressive antiviral therapy followed by administration of the …

A modeling framework for immune-related diseases

F Castiglione, S Motta, F Pappalardo… - … Modelling of Natural …, 2012 - cambridge.org
About twenty five years ago the first discrete mathematical model of the immune system was
proposed. It was very simple and stylized. Later, many other computational models have …

Modelling the FRC network of lymph node

G Bocharov, M Novkovic, L Onder… - … on Artificial Immune …, 2015 - ieeexplore.ieee.org
This work presents an idealized geometric model of the lymph node (LN) consisting of a set
of'elementary'macroscopic structures such as subcapsular sinus, trabecular sinuses with a …

[PDF][PDF] Multi-scale computer models of lymphatic pumping

CJ Morris - 2022 - core.ac.uk
The lymphatic system maintains fluid homeostasis by returning interstitial fluid to the veins.
Lymphatics pump fluid locally with contracting segments of the vessel (lymphangions) …

Timescales of the adaptive immune response

M Day, G Lythe - Mathematical Models and Immune Cell Biology, 2011 - Springer
We discuss continuum (lattice-free) and inherently stochastic models of immune cellular
interactions, using the simplest hypothesis, that cells follow Brownian paths. The timescale …

Understanding immunology via engineering design: the role of mathematical prototyping

DJ Klinke, Q Wang - Computational and Mathematical Methods …, 2012 - Wiley Online Library
A major challenge in immunology is how to translate data into knowledge given the inherent
complexity and dynamics of human physiology. Both the physiology and engineering …

Modelling the effects of lymph node swelling on T-cell response

SC Johnson, J Frattolin, LT Edgar, M Jafarnejad… - bioRxiv, 2020 - biorxiv.org
Swelling of the lymph nodes is commonly observed during the adaptive immune response,
yet its impacts on T cell trafficking and subsequent immune response are not well known. To …