Lors de l'infection par un pathogène intracellulaire, l'organisme déclenche une réponse immunitaire spécifique dont les acteurs principaux sont les lymphocytes T-CD8. Ces cellules …
This thesis presents quantitative studies of T cell and dendritic cell (DC) behaviour in mouse lymph nodes (LNs) in the naive state and following immunisation. These processes are of …
Работа посвящена разработке методов моделирования процессов распространения инфекции вирусами иммунодефицита человека (ВИЧ) и противовирусного иммунного …
La interacción antígeno-específica de los linfocitos T con células presentadoras de antígeno (APCs) conlleva importantes cambios morfológicos y funcionales en las células T …
We have developed an agent-based computer simulation framework (PathSim2) capable of modeling overall human immune system dynamics, with a focus on local cellular interactions …
“The capacity of the human mind for formulating and solving complex problems is very small compared with the size of the problem whose solution is required for objectively rational …
CC Chemokine Receptor 7 (CCR7) promotes migration of T lymphocytes into and throughout lymph nodes via ligands CCL21 and CCL19. The mechanisms by which CCR7 …
Computer simulations play an increasingly important role in bio-medical research by allowing cheap verification of conjectures and exploration of ideas. The IMMUNOGRID …