Unwinding circular RNA's role in inflammatory pulmonary diseases

AA Bhat, G Gupta, A Goyal, R Thapa… - Naunyn-Schmiedeberg's …, 2024 - Springer
Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and
cellular processes in various physiological and pathological conditions. In recent years …

Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …

Circular RNAs as emerging regulators in COVID-19 pathogenesis and progression

X Gao, D Fang, Y Liang, X Deng, N Chen… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), an infectious acute respiratory disease caused by a
newly emerging RNA virus, is a still-growing pandemic that has caused more than 6 million …

Construction of atrial fibrillation‐related circRNA/lncRNA‐miRNA‐mRNA regulatory network and analysis of potential biomarkers

J Wen, Z Ruan, F Wang, G Chen, J Zhu… - Journal of Clinical …, 2023 - Wiley Online Library
Background The specific pathogenesis of atrial fibrillation (AF) remains unclear. In this study,
we examined the expression of differential messenger RNAs (mRNAs), circular RNAs …

Functional Involvement of circRNAs in the Innate Immune Responses to Viral Infection

M Maarouf, L Wang, Y Wang, KR Rai, Y Chen, M Fang… - Viruses, 2023 - mdpi.com
Effective viral clearance requires fine-tuned immune responses to minimize undesirable
inflammatory responses. Circular RNAs (circRNAs) are a class of non-coding RNAs that are …

The hub genes and their potential regulatory mechanisms in chronic spontaneous urticaria revealed by integrated transcriptional expression analysis

R Liu, D Lv, L Cao, Y Liu, X Wen, Y Jiang… - Experimental …, 2023 - Wiley Online Library
Chronic spontaneous urticaria (CSU) is a recurrent disease characterized by wheals and or
angioedema, and its pathogenesis is still unclear. The microarray datasets of skin tissue …

CircRNA-associated ceRNA networks (circCeNETs) in chronic obstructive pulmonary disease (COPD)

Z Firoozi, A Shahi, E Mohammadisoleimani, S Afzali… - Life Sciences, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD), a chronic airway disorder, which is mostly
brought on by cigarette smoke extract (CSE), is a leading cause of death which has a high …

MicroRNAs in the Regulation of RIG-I-like Receptor Signaling Pathway: Possible Strategy for Viral Infection and Cancer

D Chen, Q Ji, J Liu, F Cheng, J Zheng, Y Ma, Y He… - Biomolecules, 2023 - mdpi.com
The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) play a crucial role as pattern-
recognition receptors within the innate immune system. These receptors, present in various …

CircRNA: a rising therapeutic strategy for lung injury induced by pulmonary toxicants

C Liao, ZW He, R Yu, YJ Yu, XR Liu, DL Kong… - Archives of …, 2024 - Springer
Lung injury has been a serious medical problem that requires new therapeutic approaches
and biomarkers. Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) that exist widely …

Advances in the understanding of circRNAs that influence viral replication in host cells

S Wang, X Li, G Liu, Z Qiu, J Wang, D Yang… - Medical Microbiology …, 2024 - Springer
Circular RNAs (circRNAs) are non-coding RNAs discovered in recent years, which are
produced by back-splicing involving the 3'and 5'ends of RNA molecules. There is increasing …