Nature-derived polymers, or biopolymers, are among the most employed materials for the development of nanocarriers. Chitosan (CS) is derived from the acetylation of chitin, and this …
This study investigates the development of topically applied non-invasive amino- functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN …
M Wassel, M Radwan, R Elghazawy - BMC Oral Health, 2023 - Springer
Background Thorough disinfection of root canals in primary molars may be complicated by the complex root canal morphology. This in-vitro study aimed to compare direct and residual …
Linezolid (LZ) loaded chitosan–nanoparticles (CSNPs) was developed by the ionic–gelation method using Tripolyphosphate–sodium as a crosslinker for topical application for the …
Positively charged NCs of TZP (0.1%, w/v) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and …
P Dahiya, A Zafar, FJ Ahmad, M Khalid, A Ali - Journal of Drug Delivery …, 2023 - Elsevier
The present study was to develop forskolin (F) and rutin (R)-loaded chitosan (CS)-coated poly lactic-co-glycolic acid (PLGA) nanoparticles (NP) for the improvement of ocular delivery …
Olaparib (OLA) is an anticancer agent that acts by inhibiting the poly (ADP-ribose)- polymerase-I (PARP-I). Due to its low solubility and low permeability, it has been placed as a …
Gram-positive bacterial infections are among the most serious diseases related with high mortality rates and huge healthcare costs especially with the rise of antibiotic-resistant …
A Zafar, OA Alsaidan, MH Elkomy, SS Imam… - Journal of Drug Delivery …, 2023 - Elsevier
The oral route is the most common route for the delivery of therapeutic agents but has limitations to poorly soluble therapeutics like intrasubject variability and low bioavailability …