Chitosan nanoparticles and based composites as a biocompatible vehicle for drug delivery: a review

R Pathak, S Bhatt, VD Punetha, M Punetha - International Journal of …, 2023 - Elsevier
The shellfish processing industry is one of the largest growing industries across the globe
with a market size of around USD 62B. However, it also leads to a significant environmental …

Eco-friendly chitosan-based nanostructures in diabetes mellitus therapy: Promising bioplatforms with versatile therapeutic perspectives

A Taheriazam, M Entezari, ZM Firouz… - Environmental …, 2023 - Elsevier
Nature-derived polymers, or biopolymers, are among the most employed materials for the
development of nanocarriers. Chitosan (CS) is derived from the acetylation of chitin, and this …

Mesoporous silica nanoparticles coated with carboxymethyl chitosan for 5-fluorouracil ocular delivery: characterization, in vitro and in vivo studies

AA Alhowyan, MA Kalam, M Iqbal, M Raish, AM El-Toni… - Molecules, 2023 - mdpi.com
This study investigates the development of topically applied non-invasive amino-
functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN …

Direct and residual antimicrobial effect of 2% chlorhexidine gel, double antibiotic paste and chitosan-chlorhexidine nanoparticles as intracanal medicaments against …

M Wassel, M Radwan, R Elghazawy - BMC Oral Health, 2023 - Springer
Background Thorough disinfection of root canals in primary molars may be complicated by
the complex root canal morphology. This in-vitro study aimed to compare direct and residual …

Topical Application of Linezolid–Loaded Chitosan Nanoparticles for the Treatment of Eye Infections

M Alkholief, MA Kalam, AK Alshememry, R Ali… - Nanomaterials, 2023 - mdpi.com
Linezolid (LZ) loaded chitosan–nanoparticles (CSNPs) was developed by the ionic–gelation
method using Tripolyphosphate–sodium as a crosslinker for topical application for the …

Fabrication and characterization of tedizolid phosphate nanocrystals for topical ocular application: improved solubilization and in vitro drug release

MA Kalam, M Iqbal, A Alshememry, M Alkholief… - Pharmaceutics, 2022 - mdpi.com
Positively charged NCs of TZP (0.1%, w/v) for ocular use were prepared by the antisolvent
precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and …

Development of Forskolin and rutin-loaded polymeric nanoparticles for enhancement of topical ocular delivery: optimization, in-vitro, ex-vivo, and toxicity evaluation

P Dahiya, A Zafar, FJ Ahmad, M Khalid, A Ali - Journal of Drug Delivery …, 2023 - Elsevier
The present study was to develop forskolin (F) and rutin (R)-loaded chitosan (CS)-coated
poly lactic-co-glycolic acid (PLGA) nanoparticles (NP) for the improvement of ocular delivery …

Nanocrystallization improves the solubilization and cytotoxic effect of a poly (Adp-ribose)-polymerase-i inhibitor

AS Alali, MA Kalam, MM Ahmed, MA Aboudzadeh… - Polymers, 2022 - mdpi.com
Olaparib (OLA) is an anticancer agent that acts by inhibiting the poly (ADP-ribose)-
polymerase-I (PARP-I). Due to its low solubility and low permeability, it has been placed as a …

Analytical methodologies for the estimation of oxazolidinone antibiotics as key members of anti-MRSA arsenal: a decade in review

EI El-Kimary, AN Allam, ES Khafagy… - Critical Reviews in …, 2023 - Taylor & Francis
Gram-positive bacterial infections are among the most serious diseases related with high
mortality rates and huge healthcare costs especially with the rise of antibiotic-resistant …

Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation

A Zafar, OA Alsaidan, MH Elkomy, SS Imam… - Journal of Drug Delivery …, 2023 - Elsevier
The oral route is the most common route for the delivery of therapeutic agents but has
limitations to poorly soluble therapeutics like intrasubject variability and low bioavailability …