Unpredictable adverse effects of herbal products

N Başaran, D Paslı, AA Başaran - Food and Chemical Toxicology, 2022 - Elsevier
Herbal products are being increasingly used all over the world for preventive and
therapeutic purposes because of the belief of their safety. They have become an important …

Pharmacogenetics and precision medicine approaches for the improvement of COVID-19 therapies

M Biswas, N Sawajan, T Rungrotmongkol… - Frontiers in …, 2022 - frontiersin.org
Many drugs are being administered to tackle coronavirus disease 2019 (COVID-19)
pandemic situations without establishing clinical effectiveness or tailoring safety. A …

Translational value of the transdermal administration of bergamot essential oil and of its fractions

D Scuteri, L Rombolà, M Crudo, C Watanabe… - Pharmaceutics, 2022 - mdpi.com
The essential oil of bergamot (BEO) has consistently proven antinociceptive and
antiallodynic properties. Accordingly, the analgesic efficacy of the decolored essential oil …

Effects of palmitoylethanolamide (PEA) on nociceptive, musculoskeletal and neuropathic pain: Systematic review and meta-analysis of clinical evidence

D Scuteri, F Guida, S Boccella, E Palazzo, S Maione… - Pharmaceutics, 2022 - mdpi.com
Some 30–50% of the global population and almost 20% of the European population actually
suffer from chronic pain, which presents a tremendous burden to society when this pain …

Focus on zavegepant: the first intranasal third-generation gepant

D Scuteri, A Tarsitano, P Tonin, G Bagetta… - Pain …, 2022 - Future Medicine
Migraine is the leading cause of years lived with disability in people under 50 and its burden
is increased by calcitonin gene-related peptide (CGRP)-driven chronicity. Newly approved …

Herb–drug interactions: Worlds intersect with the patient at the center

MB Babos, M Heinan, L Redmond, F Moiz… - Medicines, 2021 - mdpi.com
Background This review examines three bodies of literature related to herb–drug
interactions: case reports, clinical studies, evaluations found in six drug interaction checking …

Multifaceted factors causing conflicting outcomes in herb-drug interactions

YH Choi, YW Chin - Pharmaceutics, 2020 - mdpi.com
Metabolic enzyme and/or transporter-mediated pharmacokinetic (PK) changes in a drug
caused by concomitant herbal products have been a primary issue of herb and drug …

Safety of Onabotulinumtoxin A in Chronic Migraine: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

MT Corasaniti, G Bagetta, P Nicotera, A Tarsitano… - Toxins, 2023 - mdpi.com
Some 14% of global prevalence, based on high-income country populations, suffers from
migraine. Chronic migraine is very disabling, being characterized by at least 15 headache …

Herb-drug interactions and their impact on pharmacokinetics: an update

W Cheng, K Xia, S Wu, Y Li - Current Drug Metabolism, 2023 - ingentaconnect.com
Herb medicine has a long history of application and is still used worldwide. With the
development of complementary and alternative medicine, the interaction between herb and …

Analgesic characteristics of NanoBEO released by an airless dispenser for the control of agitation in severe dementia

D Scuteri, L Rombolà, T Hayashi, C Watanabe… - Molecules, 2022 - mdpi.com
Chronic pain is one of the most common causes of the need for clinical evaluation, acquiring
more importance in the elderly with cognitive impairment. Reduced self-reporting …