Progress of Wnt signaling pathway in osteoporosis

Y Gao, N Chen, Z Fu, Q Zhang - Biomolecules, 2023 - mdpi.com
Osteoporosis, one of the serious health diseases, involves bone mass loss, bone density
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …

Icariin: A promising natural product in biomedicine and tissue engineering

Z Seyedi, MS Amiri, V Mohammadzadeh… - Journal of Functional …, 2023 - mdpi.com
Among scaffolds used in tissue engineering, natural biomaterials such as plant-based
materials show a crucial role in cellular function due to their biocompatibility and chemical …

Coaxially fabricated dual‐drug loading electrospinning fibrous mat with programmed releasing behavior to boost vascularized bone regeneration

J Cui, X Yu, B Yu, X Yang, Z Fu, J Wan… - Advanced …, 2022 - Wiley Online Library
In clinical treatment, the bone regeneration of critical‐size defects is desiderated to be
solved, and the regeneration of large bone segment defects depends on early …

[HTML][HTML] Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the …

X Zhang, H Li, F Chen, Y Chen, Y Chai, J Liao… - Saudi pharmaceutical …, 2021 - Elsevier
Icariin is commonly used for the clinical treatment of osteonecrosis of the femoral head
(ONFH). miR-23a-3p plays a vital role in regulating the osteogenic differentiation of bone …

Reciprocal Effect of Environmental Stimuli to regulate the adipogenesis and Osteogenesis fate decision in bone marrow-derived mesenchymal stem cells (BM-MSCs)

X Xu, L Zhao, PD Terry, J Chen - Cells, 2023 - mdpi.com
Mesenchymal stem cells derived from bone marrow (BM-MSCs) can differentiate into
adipocytes and osteoblasts. Various external stimuli, including environmental contaminants …

Acacetin prevents bone loss by disrupting osteoclast formation and promoting type H vessel formation in ovariectomy-induced osteoporosis

X Lin, F Xu, KW Zhang, WX Qiu, H Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
Osteoporosis, characterized by the destruction of bone resorption and bone formation, is a
serious disease that endangers human health. Osteoporosis prevention and treatment has …

Critical review on anti-obesity effects of phytochemicals through Wnt/β-catenin signaling pathway

J Luo, Z Yu, J Tovar, A Nilsson, B Xu - Pharmacological Research, 2022 - Elsevier
Phytochemicals have been used as one of the sources for the development of anti-obesity
drugs. Plants are rich in a variety of bioactive compounds including polyphenols, saponins …

Integrins, cadherins and channels in cartilage mechanotransduction: perspectives for future regeneration strategies

MP Dieterle, A Husari, B Rolauffs… - Expert Reviews in …, 2021 - cambridge.org
Articular cartilage consists of hyaline cartilage, is a major constituent of the human
musculoskeletal system and has critical functions in frictionless joint movement and articular …

The potential benefits and mechanisms of protein nutritional intervention on bone health improvement

Y Yu, X Li, M Zheng, L Zhou, J Zhang… - Critical Reviews in …, 2024 - Taylor & Francis
Osteoporosis commonly occurs in the older people and severe patients, with the main
reason of the imbalance of bone metabolism (the rate of bone resorption exceeding the rate …

[HTML][HTML] The wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: An in vivo and in vitro study

Y Cai, H Sun, X Song, J Zhao, D Xu, M Liu - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Our study was performed to investigate whether the Wingless and int-1 (Wnt) signaling
pathway promotes osteogenic differentiation and inhibits apoptosis in bone marrow …