Viruses and their hosts have coevolved for a long time. This coevolution places both the
pathogen and the human immune system under selective pressure; on the one hand, the …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to coronavirus disease (COVID-19), a global health pandemic causing millions of deaths …

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Clinical presentations of COVID-19 are highly variable, yet the precise mechanisms that
govern the pathophysiology of different disease courses remain poorly defined. Across the …

The COVID-19 pandemic has caused more than three million deaths globally. The severity
of the disease is characterized, in part, by a dysregulated immune response. CD16+ …

Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) directly interacts
with host's epithelial and immune cells, leading to inflammatory response induction, which is …

(1) Background: In COVID-19 survivors there is an increased prevalence of pulmonary
fibrosis of which the underlying molecular mechanisms are poorly understood;(2) Methods …

The ongoing pandemic of severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2)
and subsequently, coronavirus disease 2019 (COVID‐19), has led to the deaths of over 6.1 …

ABSTRACT A main clinical parameter of COVID-19 pathophysiology is hypoxia. Here we
show that hypoxia decreases the attachment of the receptor-binding domain (RBD) and the …

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which induces a high
release of pro-inflammatory chemokines and cytokines, leading to severe systemic …