[HTML][HTML] Synthetic multiantigen MVA vaccine COH04S1 and variant-specific derivatives protect Syrian hamsters from SARS-CoV-2 Omicron subvariants

F Wussow, M Kha, T Kim, M Ly, M Yll-Pico, S Kar… - npj Vaccines, 2023 - nature.com
Abstract Emerging SARS-CoV-2 Omicron subvariants continue to disrupt COVID-19 vaccine
efficacy through multiple immune mechanisms including neutralizing antibody evasion. We …

mRNA bivalent booster enhances neutralization against BA. 2.75. 2 and BQ. 1.1

ME Davis-Gardner, L Lai, B Wali, H Samaha, D Solis… - Biorxiv, 2022 - biorxiv.org
The emergence of the highly divergent SARS-CoV-2 Omicron variant has jeopardized the
efficacy of vaccines based on the ancestral spike. The bivalent COVID-19 mRNA booster …

Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants

Z Ye, SR Bonam, LGA McKay… - Proceedings of the …, 2023 - National Acad Sciences
The emergence of highly transmissible severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) that are resistant to the current COVID-19 …

[HTML][HTML] Neutralization of Omicron subvariants BA. 1 and BA. 5 by a booster dose of COVID-19 mRNA vaccine in a Japanese nursing home cohort

M Itamochi, S Yazawa, N Inasaki, Y Saga, E Yamazaki… - Vaccine, 2023 - Elsevier
The sustained epidemic of Omicron subvariants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a worldwide concern, and older adults are at high risk. We …

Challenges and prospects in developing future SARS-CoV-2 vaccines: Overcoming original antigenic sin and inducing broadly neutralizing antibodies

JP Evans, SL Liu - The Journal of Immunology, 2023 - journals.aai.org
The impacts of the COVID-19 pandemic led to the development of several effective SARS-
CoV-2 vaccines. However, waning vaccine efficacy as well as the antigenic drift of SARS …

Effectiveness of BNT162b2 BA. 4/5 bivalent mRNA vaccine against symptomatic COVID-19 among immunocompetent individuals testing at a large US retail pharmacy

AE Rudolph, FL Khan, A Shah, TG Singh… - The Journal of …, 2024 - academic.oup.com
Background Data on the effectiveness of BA. 4/5 bivalent vaccine stratified by age and prior
infection are lacking. Methods This test-negative study used data from individuals≥ 5 years …

[HTML][HTML] Effectiveness of monovalent mRNA vaccines against COVID-19–associated hospitalization among immunocompetent adults during BA. 1/BA. 2 and BA. 4/BA …

D Surie - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Effectiveness of Monovalent mRNA Vaccines Against COVID-19–Associated
Hospitalization Among Immunocompetent Adults During BA.1/BA.2 and BA.4/BA.5 …

Omicron variant-specific serological imprinting following BA. 1 or BA. 4/5 bivalent vaccination and previous SARS-CoV-2 infection: A cohort study

EAM Baerends, J Reekie, SR Andreasen… - Clinical Infectious …, 2023 - academic.oup.com
Background Continuous evolution of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) outpaces monovalent vaccine cross-protection to new viral variants …

[HTML][HTML] Renewed global threat by the novel SARS-CoV-2 variants 'XBB, BF. 7, BQ. 1, BA. 2.75, BA. 4.6': A discussion

RK Mohapatra, A Mahal, LVS Kutikuppala, M Pal… - Frontiers in …, 2022 - frontiersin.org
Despite the numerous preventive and curative measures in vogue post the onset of the
recent pandemic, the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) …

Vaccine schedule recommendations and updates for patients with hematologic malignancy post‐hematopoietic cell transplant or CAR T‐cell therapy

G Reynolds, VG Hall, BW Teh - Transplant Infectious Disease, 2023 - Wiley Online Library
Revaccination after receipt of a hematopoietic cell transplant (HCT) or cellular therapies is a
pillar of patient supportive care, with the potential to reduce morbidity and mortality linked to …