Pharmacology of heparin and related drugs: An update

J Hogwood, B Mulloy, R Lever, E Gray, CP Page - Pharmacological reviews, 2023 - ASPET
Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Anticoagulants for people hospitalised with COVID‐19

RLG Flumignan, VT Civile… - Cochrane Database …, 2022 - cochranelibrary.com
Background The primary manifestation of coronavirus disease 2019 (COVID‐19) is
respiratory insufficiency that can also be related to diffuse pulmonary microthrombosis and …

[HTML][HTML] ISTH guidelines for antithrombotic treatment in COVID‐19

S Schulman, M Sholzberg, AC Spyropoulos… - Journal of Thrombosis …, 2022 - Elsevier
Antithrombotic agents reduce risk of thromboembolism in severely ill patients. Patients with
coronavirus disease 2019 (COVID‐19) may realize additional benefits from heparins …

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - Signal transduction and …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

Anticoagulation and antiplatelet therapy for prevention of venous and arterial thrombotic events in critically ill patients with COVID-19: COVID-PACT

EA Bohula, DD Berg, MS Lopes, JM Connors, I Babar… - Circulation, 2022 - Am Heart Assoc
Background: The efficacy and safety of prophylactic full-dose anticoagulation and
antiplatelet therapy in critically ill COVID-19 patients remain uncertain. Methods: COVID …

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week

ME Farkouh, GW Stone, A Lala, E Bagiella… - Journal of the American …, 2022 - jacc.org
Clinical, laboratory, and autopsy findings support an association between coronavirus
disease-2019 (COVID-19) and thromboembolic disease. Acute COVID-19 infection is …

Thromboprophylaxis in patients with COVID-19: a brief update to the CHEST guideline and expert panel report

LK Moores, T Tritschler, S Brosnahan, M Carrier… - Chest, 2022 - Elsevier
Background Patients hospitalized with COVID-19 often exhibit markers of a hypercoagulable
state and have an increased incidence of VTE. In response, CHEST issued rapid clinical …

Thromboembolic prevention and anticoagulant therapy during the COVID-19 pandemic: updated clinical guidance from the anticoagulation forum

GD Barnes, A Burnett, A Allen, J Ansell… - Journal of thrombosis …, 2022 - Springer
Thromboembolism is a common and deadly consequence of COVID-19 infection for
hospitalized patients. Based on clinical evidence pre-dating the COVID-19 pandemic and …

Clinical features of thrombosis and bleeding in COVID-19

MR Thomas, M Scully - Blood, The Journal of the American …, 2022 - ashpublications.org
Infection with the SARS-CoV-2 virus, resulting in COVID-19 disease, has presented a
unique scenario associated with high rates of thrombosis. The risk of venous thrombosis is …

Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19: a systematic review and meta …

L Ortega-Paz, M Galli, D Capodanno… - European Heart …, 2022 - academic.oup.com
Background The clinical impact of different prophylactic anticoagulation regimens among
hospitalized patients with coronavirus disease 2019 (COVID-19) remains unclear. We …