The intriguing thyroid hormones–lung cancer association as exemplification of the thyroid hormones–cancer association: Three decades of evolving research

MV Deligiorgi, DT Trafalis - International journal of molecular sciences, 2021 - mdpi.com
Exemplifying the long-pursued thyroid hormones (TH)–cancer association, the TH–lung
cancer association is a compelling, yet elusive, issue. The present narrative review provides …

Applications of graph theory in studying protein structure, dynamics, and interactions

Z Zhou, G Hu - Journal of Mathematical Chemistry, 2023 - Springer
Being a core tool, graph theory, as a mathematical formalism in mathematical chemistry, has
become an essential approach for studying the complex behavior and interactions in protein …

Optimizing weighted gene co-expression network analysis with a multi-threaded calculation of the topological overlap matrix

M Shuai, D He, X Chen - Statistical applications in genetics and …, 2021 - degruyter.com
Biomolecular networks are often assumed to be scale-free hierarchical networks. The
weighted gene co-expression network analysis (WGCNA) treats gene co-expression …

Hnrnpa2b1 as a potential therapeutic target for thymic epithelial tumor recurrence: an integrative network analysis

Z Zhou, Y Lu, Z Gu, Q Sun, W Fang, W Yan, X Ku… - Computers in Biology …, 2023 - Elsevier
Thymic epithelial tumors (TETs) are rare malignant tumors, and the molecular mechanisms
of both primary and recurrent TETs are poorly understood. Here we established …

Differential network analysis reveals the key role of the ECM-receptor pathway in α-particle-induced malignant transformation

W Yan, W Hu, Y Song, X Liu, Z Zhou, W Li… - … Therapy-Nucleic Acids, 2024 - cell.com
Space particle radiation is a major environmental factor in spaceflight, and it is known to
cause body damage and even trigger cancer, but with unknown molecular etiologies. To …

DM-MOGA: a multi-objective optimization genetic algorithm for identifying disease modules of non-small cell lung cancer

J Shang, X Zhu, Y Sun, F Li, X Kong, JX Liu - BMC bioinformatics, 2023 - Springer
Background Constructing molecular interaction networks from microarray data and then
identifying disease module biomarkers can provide insight into the underlying pathogenic …

Prognostic prediction of patients having classical papillary thyroid carcinoma with a 4 mRNA-based risk model

L Xiang, JH Zhao, Y Tang, JW Tan, LB Li, C Gong - Medicine, 2024 - journals.lww.com
The dysregulation of protein-coding genes involved in various biological functions is closely
associated with the progression of thyroid cancer. This study aimed to investigate the effects …

Identifying Lymph Node Metastasis-related Factors in Breast Cancer using Differential Modular and Mutational Structural Analysis

X Liu, B Yang, X Huang, W Yan, Y Zhang… - Interdisciplinary Sciences …, 2023 - Springer
Complex diseases are generally caused by disorders of biological networks and/or
mutations in multiple genes. Comparisons of network topologies between different disease …