[HTML][HTML] Differential functional responses of neutrophil subsets in severe COVID-19 patients
KR McLeish, R Shrestha, A Vashishta… - Frontiers in …, 2022 - frontiersin.org
Neutrophils play a significant role in determining disease severity following SARS-CoV-2
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …
Pathological effects of SARS-CoV-2 on hematological and immunological cells: Alterations in count, morphology, and function
Abstract The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the
causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million …
causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million …
Understanding the link between obesity and severe COVID-19 outcomes: causal mediation by systemic inflammatory response
AS Foulkes, C Selvaggi, D Shinnick… - The Journal of …, 2022 - academic.oup.com
Background Obesity is an established risk factor for severe COVID-19 outcomes. The
mechanistic underpinnings of this association are not well-understood. Objective To …
mechanistic underpinnings of this association are not well-understood. Objective To …
[HTML][HTML] Transcriptional changes in CD16+ monocytes may contribute to the pathogenesis of COVID-19
The COVID-19 pandemic has caused more than three million deaths globally. The severity
of the disease is characterized, in part, by a dysregulated immune response. CD16+ …
of the disease is characterized, in part, by a dysregulated immune response. CD16+ …
[HTML][HTML] Early peripheral blood MCEMP1 and HLA-DRA expression predicts COVID-19 prognosis
Background Mass vaccination has dramatically reduced the incidence of severe COVID-19,
with most cases now presenting as self-limiting upper respiratory tract infections. However …
with most cases now presenting as self-limiting upper respiratory tract infections. However …
Neutrophils at the crossroads of acute viral infections and severity
Neutrophils are versatile immune effector cells essential for mounting a first-line defense
against invading pathogens. However, uncontrolled activation can lead to severe life …
against invading pathogens. However, uncontrolled activation can lead to severe life …
[HTML][HTML] Lung protection vs. infection resolution: interleukin 10 suspected of double-dealing in COVID-19
HA Lindner, SY Velasquez, M Thiel… - Frontiers in …, 2021 - frontiersin.org
The pathological processes by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection that make the virus a major threat to global health are insufficiently …
CoV-2) infection that make the virus a major threat to global health are insufficiently …
[HTML][HTML] Peripheral blood immune profiling of convalescent plasma donors reveals alterations in specific immune subpopulations even at 2 months post SARS-CoV-2 …
N Orologas-Stavrou, M Politou, P Rousakis… - Viruses, 2020 - mdpi.com
Immune profiling of patients with COVID-19 has shown that SARS-CoV-2 causes severe
lymphocyte deficiencies (eg, lymphopenia, decreased numbers, and exhaustion of T cells) …
lymphocyte deficiencies (eg, lymphopenia, decreased numbers, and exhaustion of T cells) …
Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx
During respiratory viral infections, the precise roles of monocytes and dendritic cells (DCs) in
the nasopharynx in limiting infection and influencing disease severity are incompletely …
the nasopharynx in limiting infection and influencing disease severity are incompletely …
Immunouniverse of SARS-CoV-2
D Jiménez, M Torres Arias - Immunological Medicine, 2022 - Taylor & Francis
SARS-CoV-2 virus has become a global health problem that has caused millions of deaths
worldwide. The infection can present with multiple clinical features ranging from …
worldwide. The infection can present with multiple clinical features ranging from …