[HTML][HTML] New discovery of myeloid-derived suppressor cell's tale on viral infection and COVID-19

SJ Park, D Nam, HC Seong, YS Hahn - Frontiers in Immunology, 2022 - frontiersin.org
Myeloid-derived suppressor cells (MDSCs) are generated under biological stress such as
cancer, inflammatory tissue damage, and viral infection. In recent years, with occurrence of …

[HTML][HTML] Omega-3 polyunsaturated fatty acids (n-3 PUFAs) for Immunomodulation in COVID-19 related acute respiratory distress syndrome (ARDS)

F Velotti, L Costantini, N Merendino - Journal of Clinical Medicine, 2022 - mdpi.com
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), might be complicated by Acute Respiratory Distress …

The performance and perspectives of dendritic cell vaccines modified by immune checkpoint inhibitors or stimulants

J Ding, Y Zheng, G Wang, J Zheng, D Chai - Biochimica et Biophysica Acta …, 2022 - Elsevier
Therapeutic dendritic cell (DC) vaccines stimulate the elimination of tumor cells by the
immune system. However, while antigen-specific T cell responses induced by DC vaccines …

[HTML][HTML] Pathological roles of pulmonary cells in acute lung injury: lessons from clinical practice

N Enomoto - International Journal of Molecular Sciences, 2022 - mdpi.com
Interstitial lung diseases (ILD) are relatively rare and sometimes become life threatening. In
particular, rapidly progressive ILD, which frequently presents as acute lung injury (ALI) on …

[HTML][HTML] Obesity correlates with pronounced aberrant innate immune responses in hospitalized aged COVID-19 patients

MZ Zulu, S Sureshchandra, AN Pinski, B Doratt… - Frontiers in …, 2021 - frontiersin.org
Both age and obesity are leading risk factors for severe coronavirus disease 2019 (COVID-
19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Restoration of dendritic cell homeostasis and Type I/Type III interferon levels in convalescent COVID-19 individuals

A Rajamanickam, NP Kumar, AN Pandiaraj… - BMC immunology, 2022 - Springer
Background Plasmacytoid and myeloid dendritic cells play a vital role in the protection
against viral infections. In COVID-19, there is an impairment of dendritic cell (DC) function …

[HTML][HTML] Data-driven analysis of COVID-19 reveals persistent immune abnormalities in convalescent severe individuals

J Lim, KJ Puan, LW Wang, KWW Teng, CY Loh… - Frontiers in …, 2021 - frontiersin.org
Severe SARS-CoV-2 infection can trigger uncontrolled innate and adaptive immune
responses, which are commonly associated with lymphopenia and increased neutrophil …

[HTML][HTML] Proteomic and single-cell transcriptomic dissection of human plasmacytoid dendritic cell response to influenza virus

MH Ghanem, AJ Shih, H Khalili, LM Brown… - Frontiers in …, 2022 - frontiersin.org
Plasmacytoid dendritic cells [pDCs] represent a rare innate immune subset uniquely
endowed with the capacity to produce substantial amounts of type-I interferons. This function …

[HTML][HTML] Persisting IL-18 levels after COVID-19 correlate with markers of cardiovascular inflammation reflecting potential risk of CVDs development

I Andrejčinová, G Blažková, I Papatheodorou… - Heliyon, 2024 - cell.com
COVID-19 manifestation is associated with a strong immune system activation leading to
inflammation and subsequently affecting the cardiovascular system. The objective of the …

Increased B‐cell activity with consumption of activated monocytes in severe COVID‐19 patients

I Kos, B Balensiefer, V Lesan… - European journal of …, 2021 - Wiley Online Library
The pathogenesis of autoimmune complications triggered by SARS‐CoV2 has not been
completely elucidated. Here, we performed an analysis of the cellular immune status, cell …