The laminar microstructure of the cerebral cortex has distinct anatomical characteristics of the development, function, connectivity, and even various pathologies of the brain. In recent …
Network control theory (NCT) is a simple and powerful tool for studying how network topology informs and constrains dynamics. Compared to other structure-function coupling …
Theories of consciousness suggest that brain mechanisms underlying transitions into and out of unconsciousness are conserved no matter the context or precipitating conditions. We …
Dynamics play a critical role in computation. The principled evolution of states over time enables both biological and artificial networks to represent and integrate information to …
Patterns of neural activity underlie human cognition. Transitions between these patterns are orchestrated by the brain's network architecture. What are the mechanisms linking network …
The aging brain undergoes major changes in its topology. The mechanisms by which the brain mitigates age-associated changes in topology to maintain robust control of brain …
The human brain is a complex system with high metabolic demands and extensive connectivity that requires control to balance energy consumption and functional efficiency …
SP Singleton, P Velidi, L Schilling, AI Luppi… - Biological Psychiatry …, 2024 - Elsevier
Background Heavy alcohol use (HAU) and its associated conditions, such as alcohol use disorder (AUD), impact millions of individuals worldwide. While our understanding of the …
Understanding how the brain's macroscale dynamics are shaped by underlying microscale mechanisms is a key problem in neuroscience. In animal models, we can now investigate …