[HTML][HTML] T cell immunity to SARS-CoV-2

J Niessl, T Sekine, M Buggert - Seminars in immunology, 2021 - Elsevier
Exceptional efforts have been undertaken to shed light into the biology of adaptive immune
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …

[HTML][HTML] SARS-CoV-2 infection and COVID-19 vaccination in cancer patients undergoing immune checkpoint inhibitors

Y Yang, G Xu - Cell Death & Disease, 2023 - nature.com
Cancer patients are susceptible to severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2). Different antitumor treatments have attracted wide attention in the context of …

SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19

C Cai, Y Gao, S Adamo, O Rivera-Ballesteros… - Science …, 2023 - science.org
T cells are critical for immune protection against severe COVID-19, but it has remained
unclear whether repeated exposure to SARS-CoV-2 antigens delivered in the context of …

[HTML][HTML] Impaired function and delayed regeneration of dendritic cells in COVID-19

E Winheim, L Rinke, K Lutz, A Reischer… - PLoS …, 2021 - journals.plos.org
Disease manifestations in COVID-19 range from mild to severe illness associated with a
dysregulated innate immune response. Alterations in function and regeneration of dendritic …

[HTML][HTML] Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunities

M Alahdal, E Elkord - Clinical Immunology, 2022 - Elsevier
Exhaustion of immune cells in COVID-19 remains a serious concern for infection
management and therapeutic interventions. As reported, immune cells such as T effector …

Analysis of SARS-CoV-2 isolates, namely the Wuhan strain, Delta variant, and Omicron variant, identifies differential immune profiles

S Shahbaz, N Bozorgmehr, J Lu, M Osman… - Microbiology …, 2023 - Am Soc Microbiol
There is an urgent need to better understand the impact of different severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants on immune response and disease …

[HTML][HTML] Galectin-9 promotes natural killer cells activity via interaction with CD44

A Rahmati, S Bigam, S Elahi - Frontiers in Immunology, 2023 - frontiersin.org
Natural killer (NK) cells are a potent innate source of cytokines and cytoplasmic granules.
Their effector functions are tightly synchronized by the balance between the stimulatory and …

[HTML][HTML] Implications of NKG2A in immunity and immune-mediated diseases

X Wang, H Xiong, Z Ning - Frontiers in immunology, 2022 - frontiersin.org
In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer
(NK) cells and CD8+ T cells. It form heterodimer receptors with CD94, and targets the …

[HTML][HTML] Depletion of polyfunctional CD26highCD8+ T cells repertoire in chronic lymphocytic leukemia

N Bozorgmehr, M Hnatiuk, AC Peters… - … Hematology & Oncology, 2023 - Springer
Background CD8+ T cells play an essential role against tumors but the role of human CD8+
CD26+ T cell subset against tumors, in particular, haematological cancers such as chronic …

[HTML][HTML] Polyfunctional CD4 T-cells correlating with neutralising antibody is a hallmark of COVISHIELDTM and COVAXIN® induced immunity in COVID-19 exposed …

S Rakshit, S Babji, C Parthiban, R Madhavan, V Adiga… - npj Vaccines, 2023 - nature.com
Detailed characterisation of immune responses induced by COVID-19 vaccines rolled out in
India: COVISHIELDTM (CS) and COVAXIN®(CO) in a pre-exposed population is only …