Identification of bioactive metabolites using activity metabolomics
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
Analytical methods in untargeted metabolomics: state of the art in 2015
Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …
molecule composition of biofluids and tissues, and is actually one of the most rapidly …
Bioaccumulation of therapeutic drugs by human gut bacteria
Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …
the systematic mapping of the interactions between drugs and bacteria has only started …
Alterations of host-gut microbiome interactions in multiple sclerosis
Background Multiple sclerosis (MS) has a complex genetic, immune and metabolic
pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis …
pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis …
Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and …
EA Thévenot, A Roux, Y Xu, E Ezan… - Journal of proteome …, 2015 - ACS Publications
Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …
toxicology. As a consequence, characterization of the variations of the urine metabolome …
Reprogramming of plant central metabolism in response to abiotic stresses: A metabolomics view
Y Xu, X Fu - International Journal of Molecular Sciences, 2022 - mdpi.com
Abiotic stresses rewire plant central metabolism to maintain metabolic and energy
homeostasis. Metabolites involved in the plant central metabolic network serve as a hub for …
homeostasis. Metabolites involved in the plant central metabolic network serve as a hub for …
Mass spectral databases for LC/MS-and GC/MS-based metabolomics: State of the field and future prospects
At present, mass spectrometry (MS)-based metabolomics has been widely used to obtain
new insights into human, plant, and microbial biochemistry; drug and biomarker discovery; …
new insights into human, plant, and microbial biochemistry; drug and biomarker discovery; …
Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …
products, particularly in the field of drug discovery. While microbes have been shown to …
Using MetaboAnalyst 4.0 for metabolomics data analysis, interpretation, and integration with other omics data
Abstract MetaboAnalyst (www. metaboanalyst. ca) is an easy-to-use, comprehensive web-
based tool, freely available for metabolomics data processing, statistical analysis, functional …
based tool, freely available for metabolomics data processing, statistical analysis, functional …
Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses
XCMS Online (xcmsonline. scripps. edu) is a cloud-based informatic platform designed to
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …