The role of macrophages in the development of acute and chronic inflammatory lung diseases

JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
Macrophages play an important role in the innate and adaptive immune responses of organ
systems, including the lungs, to particles and pathogens. Cumulative results show that …

An update review of globally reported SARS-CoV-2 vaccines in preclinical and clinical stages

H Motamedi, MM Ari, S Dashtbin, M Fathollahi… - International …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the rapidly spreading pandemic COVID-19 in the world. As an effective therapeutic strategy …

Macrophage biomimetic nanocarriers for anti-inflammation and targeted antiviral treatment in COVID-19

Q Tan, L He, X Meng, W Wang, H Pan, W Yin… - Journal of …, 2021 - Springer
Background The worldwide pandemic of COVID-19 remains a serious public health menace
as the lack of efficacious treatments. Cytokine storm syndrome (CSS) characterized with …

RETRACTED: effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic SARS-CoV-2 infected subjects: a pilot clinical trial in Lebanon

AA Samaha, H Mouawia, M Fawaz, H Hassan… - Viruses, 2021 - mdpi.com
Objective: This study was designed to determine the efficacy of ivermectin, an FDA-
approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 …

Severe COVID-19 recovery is associated with timely acquisition of a myeloid cell immune-regulatory phenotype

AC Trombetta, GB Farias, AMC Gomes… - Frontiers in …, 2021 - frontiersin.org
After more than one year since the COVID-19 outbreak, patients with severe disease still
constitute the bottleneck of the pandemic management. Aberrant inflammatory responses …

Tryptophan metabolites and aryl hydrocarbon receptor in severe acute respiratory syndrome, coronavirus-2 (SARS-CoV-2) pathophysiology

G Anderson, A Carbone, G Mazzoccoli - International journal of molecular …, 2021 - mdpi.com
The metabolism of tryptophan is intimately associated with the differential regulation of
diverse physiological processes, including in the regulation of responses to severe acute …

[HTML][HTML] Chronic inflammation, neuroglial dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID …

AM Chaves-Filho, O Braniff, A Angelova, Y Deng… - Brain Research …, 2023 - Elsevier
After five waves of coronavirus disease 2019 (COVID-19) outbreaks, it has been recognized
that a significant portion of the affected individuals developed long-term debilitating …

Papel del sistema inmune en la infección por el SARS-CoV-2: inmunopatología de la COVID-19

JM Sanz, AMG Lahoz, RO Martín - Medicine-Programa de Formación …, 2021 - Elsevier
El sistema inmune es capaz de controlar adecuadamente la infección por el SARS-CoV-2
en un 81% de los pacientes, cursando de una forma asintomática o con sintomatología …

Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages …

Y Li, B Li, P Wang, Q Wang - Frontiers in Pharmacology, 2021 - frontiersin.org
Background and Aims: Qingfei Paidu decoction (QPD) and Xuanfei Baidu decoction (XBD)
are two typical traditional Chinese medicines with proven efficacy for the treatment of SARS …

In silico designing and immunoinformatics analysis of a novel peptide vaccine against metallo-beta-lactamase (VIM and IMP) variants

H Motamedi, A Alvandi, M Fathollahi, MM Ari… - PLoS …, 2023 - journals.plos.org
The rapid spread of acquired metallo-beta-lactamases (MBLs) among gram negative
pathogens is becoming a global concern. Improper use of broad-spectrum antibiotics can …