Elucidating salient site-specific functional connectivity features and site-invariant biomarkers in schizophrenia via deep neural networks

YH Chan, WC Yew, QH Chew, K Sim… - Scientific Reports, 2023 - nature.com
Schizophrenia is a highly heterogeneous disorder and salient functional connectivity (FC)
features have been observed to vary across study sites, warranting the need for methods …

Investigation of choroid plexus variability in schizophrenia-spectrum disorders–insights from a multimodal study

V Yakimov, J Moussiopoulou, L Roell, MS Kallweit… - medRxiv, 2023 - medrxiv.org
Background and Hypothesis: Previous studies have suggested that choroid plexus (ChP)
enlargement occurs in individuals with schizophrenia-spectrum disorders (SSD) and is …

How to measure functional connectivity using resting-state fMRI? A comprehensive empirical exploration of different connectivity metrics

L Roell, S Wunderlich, D Roell, F Raabe, E Wagner… - bioRxiv, 2024 - biorxiv.org
Background: Functional connectivity in the context of functional magnetic resonance
imaging is typically quantified by Pearson or partial correlation between regional time series …

[HTML][HTML] Signature of altered retinal microstructures and electrophysiology in schizophrenia spectrum disorders is associated with disease severity and polygenic risk

E Boudriot, V Gabriel, D Popovic, P Pingen… - Biological …, 2024 - Elsevier
BACKGROUND Optical coherence tomography (OCT) and electroretinography (ERG)
studies have revealed structural and functional retinal alterations in individuals with …

[HTML][HTML] Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment

FJ Raabe, A Hausruckinger, M Gagliardi, R Ahmad… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Schizophrenia (SCZ) is a genetically heterogenous psychiatric disorder of highly polygenic
nature. Correlative evidence from genetic studies indicate that the aggregated effects of …

Management von Therapieresistenzen–therapieresistente Schizophrenie

E Wagner, S Borgwardt, A Hasan - Der Nervenarzt, 2024 - Springer
Trotz enorm hoher Prävalenz und substanzieller Beeinträchtigungen der Betroffenen ist die
therapieresistente Schizophrenie (TRS) in der klinischen Forschung im Bereich …

Stadiengerechte Diagnostik und Behandlung von Makulopathien aus dem pachychoroidalen Erkrankungsspektrum

B Schworm - 2024 - edoc.ub.uni-muenchen.de
Das pachychoroidale Erkrankungsspektrum umfasst eine Reihe von Erkrankungen des
Auges, bei der es durch eine Überlastung des venösen Schenkels der choroidalen …