Catalyzing electrosynthesis: a homogeneous electrocatalytic approach to reaction discovery

JC Siu, N Fu, S Lin - Accounts of chemical research, 2020 - ACS Publications
Conspectus Electrochemistry has been used as a tool to drive chemical reactions for over
two centuries. With the help of an electrode and a power source, chemists are bestowed with …

Cleavage of carbon–carbon bonds by radical reactions

P Sivaguru, Z Wang, G Zanoni, X Bi - Chemical Society Reviews, 2019 - pubs.rsc.org
In recent years, radical C–C bond cleavage reactions have been increasingly understood
and used to perform transformations that complement traditional ionic processes. However …

Energy transfer-enabled unsymmetrical diamination using bifunctional nitrogen-radical precursors

G Tan, M Das, R Kleinmans, F Katzenburg… - Nature Catalysis, 2022 - nature.com
Vicinal diamines, especially unsymmetrical ones, are among the most common structural
motifs in biologically active molecules, natural products and pharmaceuticals. While the …

Cu-electrocatalytic diazidation of alkenes at ppm catalyst loading

CY Cai, YT Zheng, JF Li, HC Xu - Journal of the American …, 2022 - ACS Publications
The 1, 2-diamine motif is prevalent in natural products, small-molecule pharmaceuticals, and
catalysts for asymmetric synthesis. Transition metal catalyzed alkene diazidation has …

Metal-catalyzed electrochemical diazidation of alkenes

N Fu, GS Sauer, A Saha, A Loo, S Lin - Science, 2017 - science.org
Vicinal diamines are a common structural motif in bioactive natural products, therapeutic
agents, and molecular catalysts, motivating the continuing development of efficient …

An electrocatalytic approach to the radical difunctionalization of alkenes

GS Sauer, S Lin - ACS Catalysis, 2018 - ACS Publications
Given its many distinct characteristics, electrochemistry represents an attractive approach to
meet the prevailing trends in organic synthesis. In particular, electrocatalysis—a process that …

Reductive Coupling of Nitroarenes and HCHO for General Synthesis of Functional Ethane-1, 2-diamines by a Cobalt Single-Atom Catalyst

JL Sun, H Jiang, PH Dixneuf… - Journal of the American …, 2023 - ACS Publications
Despite the extensive applications, selective and diverse access to N, N′-diarylethane-1, 2-
diamines remains, to date, a challenge. Here, by developing a bifunctional cobalt single …

Photochemical diazidation of alkenes enabled by ligand-to-metal charge transfer and radical ligand transfer

KJ Bian, SC Kao, D Nemoto Jr, XW Chen… - Nature …, 2022 - nature.com
Vicinal diamines are privileged synthetic motifs in chemistry due to their prevalence and
powerful applications in bioactive molecules, pharmaceuticals, and ligand design for …

Catalytic dehydrogenative cross-coupling: forming carbon− carbon bonds by oxidizing two carbon− hydrogen bonds

CS Yeung, VM Dong - Chemical reviews, 2011 - ACS Publications
Inspired by the need for green and sustainable chemistry,(1) synthetic chemists seek more
efficient ways to construct carbon− carbon (C− C) bonds, the essential link in all organic …

Ligand-Controlled NiH-Catalyzed Regiodivergent and Enantioselective Hydroamination of Alkenyl Amides

L Xie, J Liang, H Bai, X Liu, X Meng, YQ Xu… - ACS …, 2023 - ACS Publications
Transition-metal-catalyzed remote hydrofunctionalization of alkenes remains an efficient but
challenging protocol in chemical synthesis. Herein, we reported a ligand-controlled …