Mitochondrial dysfunction has important roles in the pathogenesis of AKI, yet therapeutic
approaches to improve mitochondrial function remain limited. In this study, we investigated …

Previous work has reported the important links between cellular bioenergetics and the
development of chronic kidney disease, highlighting the potential for targeting metabolic …

Ethnopharmacological relevance The combination of Astragalus membranaceus and Salvia
miltiorrhiza (AS) is an effective prescription that is widely used to treat chronic kidney …

MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level.
They are involved in intercellular communication and crosstalk between different organs. As …

MicroRNAs (miRNA) are endogenously produced short noncoding regulatory RNAs that can
repress gene expression by posttranscriptional mechanisms. They can therefore influence …

The knowledge about non-coding RNAs (ncRNAs) is rapidly increasing with new data
continuously emerging, regarding their diverse types, applications, and roles. Particular …

Diabetic nephropathy (DN) is one of the most common microvascular complications in
diabetic patients; it is also an important cause of renal dysfunction, renal fibrosis, and end …

Alport syndrome (AS) is the most frequent inherited kidney disease after autosomal
dominant polycystic kidney disease. It has three different patterns of inheritance—autosomal …

Extracellular vesicles (EV s) are nanosized, membrane‐bound vesicles released from
different cells. Recent studies have revealed that EV s may participate in renal tissue …

The podocyte is a key component of the glomerular filtration barrier. Podocyte dysfunction is
central to the underlying pathophysiology of many common glomerular diseases, including …