Summary Fragile X Syndrome (FXS) is a commonly inherited form of intellectual disability
and one of the leading genetic causes for autism spectrum disorder. Clinical symptoms of …

Brains are constantly flooded with sensory information that needs to be filtered at the pre-
attentional level and integrated into endogenous activity in order to allow for detection of …

Animal models provide preclinical tools to investigate the causal role of genetic mutations
and environmental factors in the etiology of autism spectrum disorder (ASD). Knockout and …

The prefrontal cortex (PFC), seat of the highest-order cognitive functions, constitutes a
conglomerate of highly specialized brain areas and has been implicated to have a role in …

Background. Individuals with autism spectrum disorders (ASDs) are characterized by social
communication difficulties and behavioural rigidity. Difficulties in learning from others are …

Autism spectrum disorders (ASD) are complex neurodevelopmental disorders that are
caused by genetic and/or environmental impacts, often probably by the interaction of both …

Fragile X syndrome (FXS) is an inherited form of intellectual disability and autism. Among
other symptoms, FXS patients demonstrate abnormalities in sensory processing and …

Functional genetic analyses in mice rely on efficient and in-depth characterization of the
behavioral spectrum. Automated home-cage observation can provide a systematic and …

Fragile X syndrome is a genetic condition resulting from FMR1 gene mutation that leads to
intellectual disability, autism-like symptoms, and sensory hypersensitivity. Arbaclofen, a …

Fragile X Syndrome (FXS) is the best-known form of inherited mental retardation caused by
the loss-of-function mutation in a single gene. The FMR1 gene mutation abolishes the …