Introduction Autism spectrum disorder (ASD) is a persistent neurodevelopmental condition
characterized by two core behavioral symptoms: impaired social communication and …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects an
individual's reciprocal social interaction and communication ability. Numerous genetic and …

Fragile X Syndrome (FX) is generally considered a developmental disorder, arising from a
mutation that disrupts the transcription of Fragile X Mental Retardation Protein (FMRP) …

Changes in excitation and inhibition are associated with the pathobiology of
neurodevelopmental disorders of intellectual disability and autism and are widely described …

Angelman syndrome (AS) is a single-gene neurodevelopmental disorder associated with
cognitive and motor impairment, seizures, lack of speech, and disrupted sleep. AS is caused …

Fragile X (FX) is the most common genetic cause of intellectual disability and autism.
Previous studies have shown that partial inhibition of metabotropic glutamate receptor …

This study examined the effect of knockout of KCNMA1 gene, coding for the BK channel, on
cognitive and attentional functions in mice, with an aim to better understand its implications …

Fragile X syndrome is a neurodevelopmental disorder characterized by mild-to-severe
cognitive deficits. The complete absence of Fmr1 and its protein product in the mouse model …

Highlights•ADHD mouse models have diversified due to the progress in human
genetics.•Causal genes act on monoaminergic signaling, synaptic plasticity, and …

The final maturation of the prefrontal cortex (PFC) continues into early adulthood and is
delayed compared with other forebrain structures. However, how these late onset changes …