Advances and highlights in biomarkers of allergic diseases
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …
The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
The airway epithelium—A central player in asthma pathogenesis
J Calvén, E Ax, M Rådinger - International Journal of Molecular Sciences, 2020 - mdpi.com
Asthma is a chronic inflammatory airway disease characterized by variable airflow
obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the …
obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the …
Recent miRNA research in asthma
R Sharma, A Tiwari, MJ McGeachie - Current allergy and asthma reports, 2022 - Springer
Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …
Multi-omics profiling approach to asthma: an evolving paradigm
Y Gautam, E Johansson, TB Mersha - Journal of personalized medicine, 2022 - mdpi.com
Asthma is a complex multifactorial and heterogeneous respiratory disease. Although
genetics is a strong risk factor of asthma, external and internal exposures and their …
genetics is a strong risk factor of asthma, external and internal exposures and their …
Serum exosome inflamma‐miRs are surrogate biomarkers for asthma phenotype and severity
S Vázquez‐Mera, L Martelo‐Vidal, P Miguéns‐Suárez… - Allergy, 2023 - Wiley Online Library
Background Asthma is a heterogeneous disease with several phenotypes, endotypes and
severity degrees, in which different T‐cell subpopulations are involved. These cells express …
severity degrees, in which different T‐cell subpopulations are involved. These cells express …
Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …
Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells
Bacterial extracellular vesicles (EVs) have been shown to regulate various pulmonary
diseases, but their functions in asthma remain uncertain. To demonstrate the clinical …
diseases, but their functions in asthma remain uncertain. To demonstrate the clinical …
MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis
S Wen, F Li, Y Tang, L Dong, Y He, Y Deng… - Frontiers in …, 2023 - frontiersin.org
Although M2 macrophages are involved in the orchestration of type 2 inflammation in
allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …
allergic diseases, the mechanisms underlying non-coding RNA (ncRNA)-mediated …
Sex differences in airway remodeling and inflammation: clinical and biological factors
CD Ekpruke, P Silveyra - Frontiers in Allergy, 2022 - frontiersin.org
Asthma is characterized by an increase in the contraction and inflammation of airway
muscles, resulting in airflow obstruction. The prevalence of asthma is lower in females than …
muscles, resulting in airflow obstruction. The prevalence of asthma is lower in females than …