Tixagevimab/cilgavimab in SARS-CoV-2 prophylaxis and therapy: A comprehensive review of clinical experience

K Akinosoglou, EA Rigopoulos, G Kaiafa, S Daios… - Viruses, 2022 - mdpi.com
Effective treatments and vaccines against COVID-19 used in clinical practice have made a
positive impact on controlling the spread of the pandemic, where they are available …

Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: Systematic review and network meta-analysis

M Zur, T Peselev, S Yanko, V Rotshild, I Matok - Antiviral Research, 2023 - Elsevier
Background Remdesivir, molnupiravir, and nirmatrelvir/ritonavir are three antiviral agents
approved by FDA emergency authorization for treating mild to moderate symptomatic COVID …

NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins

I Tsukalov, I Sánchez-Cerrillo, O Rajas… - Nature …, 2024 - nature.com
Increased recruitment of transitional and non-classical monocytes in the lung during SARS-
CoV-2 infection is associated with COVID-19 severity. However, whether specific innate …

COVID-19: An Update on the Latest Therapeutic Agents

KY Loo, LTH Tan, JWF Law, KW Hong… - Progress In Microbes …, 2023 - hh-publisher.com
The COVID-19 pandemic has plagued the world for over three years since discovering the
causative virus, SARS-CoV-2, in China. The rampant spread of the virus led to the loss of …

Liver Involvement during SARS-CoV-2 Infection Is Associated with a Worse Respiratory Outcome in COVID-19 Patients

C Romano, D Cozzolino, R Nevola, M Abitabile… - Viruses, 2023 - mdpi.com
Coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), may be complicated by life-threatening interstitial pneumonia …

A multidimensional approach to older patients during COVID-19 pandemic: a position paper of the special interest group on comprehensive geriatric assessment of …

A Pilotto, C Custodero, K Palmer… - European Geriatric …, 2023 - Springer
Purpose The COVID-19 pandemic has been a dramatic trigger that has challenged the
intrinsic capacity of older adults and of society. Due to the consequences for the older …

Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator

J Gauvin, DN Huynh, I Dubuc, C Lê… - Frontiers in …, 2024 - frontiersin.org
The scientific and medical community faced an unprecedented global health hazard that led
to nearly 7 million deaths attributable to the rapid spread of severe acute respiratory …

Preclinical discovery and development of nirmatrelvir/ritonavir combinational therapy for the treatment of COVID-19 and the lessons learned from SARS-COV-2 …

P Pagliano, A Spera, C Sellitto, G Scarpati… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Nirmatrelvir/ritonavir (Paxlovid®) represent an oral antiviral therapy
approved for the treatment of COVID-19. Extensive in vitro and in vivo studies have reported …

SARS-CoV-2 neurovascular invasion supported by Mendelian randomization

Y Pan, J Zhang, T He - Journal of Translational Medicine, 2024 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to
affect vessels and nerves and can be easily visualized in the retina. However, the effect of …

Indoor Inactivation of SARS-CoV-2 Virus by Liquid Hyperoxygen

G Barco, Z Khalid, A Pulliero, C Angelinetta, U Prati… - Pathogens, 2024 - mdpi.com
The possible future emergence of new SARS-CoV-2 virus variants pushes the development
of new chemoprophylaxis protocols complementary to the unspecific and specific immune …