[HTML][HTML] Biological mechanisms underpinning the development of long COVID

R Perumal, L Shunmugam, K Naidoo, D Wilkins… - Iscience, 2023 - cell.com
As COVID-19 evolves from a pandemic to an endemic disease, the already staggering
number of people that have been or will be infected with SARS-CoV-2 is only destined to …

Characterization of long COVID temporal sub-phenotypes by distributed representation learning from electronic health record data: a cohort study

A Dagliati, ZH Strasser, ZSH Abad, JG Klann… - …, 2023 - thelancet.com
Summary Background Characterizing Post-Acute Sequelae of COVID (SARS-CoV-2
Infection), or PASC has been challenging due to the multitude of sub-phenotypes, temporal …

[HTML][HTML] Risk factors and clinical presentations of long COVID in Africa: A scoping review.

E Moyo, M Chimene, P Moyo, G Musuka… - Journal of Infection and …, 2023 - Elsevier
ABSTRACT COVID-19-related complications can last for years, even in patients who are
asymptomatic during the acute phase, a phenomenon referred to as long COVID. This …

Autoantibodies to interferons in infectious diseases

E Quiros-Roldan, A Sottini, SG Signorini, F Serana… - Viruses, 2023 - mdpi.com
Anti-cytokine autoantibodies and, in particular, anti-type I interferons are increasingly
described in association with immunodeficient, autoimmune, and immune-dysregulated …

Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The STOP-PASC Randomized Clinical Trial

LN Geng, H Bonilla, H Hedlin, KB Jacobson… - JAMA Internal …, 2024 - jamanetwork.com
Importance There is an urgent need to identify treatments for postacute sequelae of SARS-
CoV-2 infection (PASC). Objective To assess the efficacy of a 15-day course of nirmatrelvir …

Meta-analysis of the impact of physical activity on the recovery of physical function in COVID-19 patients

G Yang, Z Li, Z Li, L Huang, P Liang, L Liu, D Li - Heliyon, 2023 - cell.com
Background The decrease in physical function resulting from COVID-19 infection exerts a
substantial negative influence on the quality of life of individuals. Physical activity plays a …

COVID-19 and Alzheimer's Disease Share Common Neurological and Ophthalmological Manifestations: A Bidirectional Risk in the Post-Pandemic Future

G Amadoro, V Latina, E Stigliano, A Micera - Cells, 2023 - mdpi.com
A growing body of evidence indicates that a neuropathological cross-talk takes place
between the coronavirus disease 2019 (COVID-19)-the pandemic severe pneumonia that …

Low growth hormone secretion associated with post-acute sequelae SARS-CoV-2 infection (PASC) neurologic symptoms: A case-control pilot study

TJ Wright, RB Pyles, M Sheffield-Moore… - Molecular and Cellular …, 2024 - Elsevier
Objective To determine if patients that develop lingering neurologic symptoms of fatigue and
“brain fog” after initial recovery from coronavirus disease 2019 (COVID-19) have persistent …

The predictors of long COVID in southeastern Italy

VN Quaranta, A Portacci, S Dragonieri… - Journal of Clinical …, 2023 - mdpi.com
Introduction: Long COVID is now recognized as a common consequence of the SARS-CoV-
2 infection, but we are still far from fully understanding its pathogenesis and predictive …

Hypothesis: inflammatory acid-base disruption underpins Long Covid

V van der Togt, JS Rossman - Frontiers in Immunology, 2023 - frontiersin.org
The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently
unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause …