[HTML][HTML] SARS-CoV-2 infection and immune responses

R Harne, B Williams, HFM Abdelaal, SL Baldwin… - AIMS …, 2023 - ncbi.nlm.nih.gov
The recent pandemic caused by the SARS-CoV-2 virus continues to be an enormous global
challenge faced by the healthcare sector. Availability of new vaccines and drugs targeting …

Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with asymptomatic or mild SARS-CoV-2 disease course

AD Hoeggerl, V Nunhofer, W Lauth, N Badstuber… - BMC Infectious …, 2023 - Springer
Abstract Purpose Post-COVID-19-Syndrome (PCS) frequently occurs after an infection with
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, the …

Animal models to study the neurological manifestations of the post-COVID-19 condition

C Usai, L Mateu, C Brander, J Vergara-Alert, J Segalés - Lab Animal, 2023 - nature.com
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have experienced persistent or relapsing multi-systemic symptoms months …

Have Diagnostics, Therapies, and Vaccines Made the Difference in the Pandemic Evolution of COVID-19 in Comparison with “Spanish Flu”?

F Lista, MS Peragallo, R Biselli, R De Santis, S Mariotti… - Pathogens, 2023 - mdpi.com
In 1918 many countries, but not Spain, were fighting World War I. Spanish press could report
about the diffusion and severity of a new infection without censorship for the first-time, so that …

Clinical Translation of Aptamers for COVID-19

Y Zhang, Y Li - Journal of Medicinal Chemistry, 2023 - ACS Publications
The COVID-19 etiologic agent, SARS-CoV-2, continues to be one of the leading causes of
death on a global scale. Although efficient methods for diagnosis and treatment of COVID-19 …

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

R Gheorghita, I Soldanescu, A Lobiuc… - Frontiers in …, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been
defined as the greatest global health and socioeconomic crisis of modern times. While most …

Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections

SJ Hurwitz, R De, JC LeCher, JA Downs-Bowen… - Viruses, 2024 - mdpi.com
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …

Beyond the acute illness: Exploring long COVID and its impact on multiple organ systems

N Bhattacharjee, P Sarkar, T Sarkar - Physiology International, 2023 - akjournals.com
Unprecedented worldwide health catastrophe due to the COVID-19 pandemic has ended up
resulting in high morbidity and mortality rates. Even though many people recover from acute …

Impact of Long Covid on the school experiences of children and young people: a qualitative study

A MacLean, C Wild, K Hunt, S Nettleton, ZC Skea… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To explore the impact of Long Covid (LC) on the school experiences of children
and young people (CYP). Design Qualitative study using narrative interviews. Participants …

The Role of Pentraxin 3 in Gastrointestinal Cancers

M Zajkowska, B Mroczko - Cancers, 2023 - mdpi.com
Simple Summary Gastrointestinal (GI) cancers are all malignant lesions affecting the
esophagus, stomach, liver and intrahepatic bile ducts, gallbladder, pancreas, and small and …