[HTML][HTML] The Lancet Commission on lessons for the future from the COVID-19 pandemic
Executive summary As of May 31, 2022, there were 6· 9 million reported deaths and 17· 2
million estimated deaths from COVID-19, as reported by the Institute for Health Metrics and …
million estimated deaths from COVID-19, as reported by the Institute for Health Metrics and …
[HTML][HTML] Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
[HTML][HTML] FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation
C Junqueira, Â Crespo, S Ranjbar, LB De Lacerda… - Nature, 2022 - nature.com
SARS-CoV-2 can cause acute respiratory distress and death in some patients. Although
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …
[HTML][HTML] Design of therapeutic biomaterials to control inflammation
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
[HTML][HTML] An expanded lexicon for the ubiquitin code
I Dikic, BA Schulman - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Our understanding of the ubiquitin code has greatly evolved from conventional E1, E2 and
E3 enzymes that modify Lys residues on specific substrates with a single type of ubiquitin …
E3 enzymes that modify Lys residues on specific substrates with a single type of ubiquitin …
[HTML][HTML] Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19
Background Long-COVID refers to a variety of symptoms affecting different organs reported
by people following Coronavirus Disease 2019 (COVID-19) infection. To date, there have …
by people following Coronavirus Disease 2019 (COVID-19) infection. To date, there have …
[HTML][HTML] mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
[HTML][HTML] SARS-CoV-2 variants, vaccines, and host immunity
P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
Long COVID: an overview
AV Raveendran, R Jayadevan… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aims Long COVID is the collective term to denote persistence of symptoms
in those who have recovered from SARS-CoV-2 infection. Methods WE searched the …
in those who have recovered from SARS-CoV-2 infection. Methods WE searched the …
[HTML][HTML] SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …