Management of post-acute covid-19 in primary care

T Greenhalgh, M Knight, M Buxton, L Husain - bmj, 2020 - bmj.com
Post-acute covid-19 (“long covid”) seems to be a multisystem disease, sometimes occurring
after a relatively mild acute illness. 1 Clinical management requires a whole-patient …

Persistent symptoms after Covid-19: qualitative study of 114 “long Covid” patients and draft quality principles for services

E Ladds, A Rushforth, S Wieringa, S Taylor… - BMC health services …, 2020 - Springer
Background Approximately 10% of patients with Covid-19 experience symptoms beyond 3–
4 weeks. Patients call this “long Covid”. We sought to document such patients' lived …

SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway

S Khan, MS Shafiei, C Longoria, JW Schoggins… - Elife, 2021 - elifesciences.org
The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however,
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

NF‐κB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

A comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics

L Forchette, W Sebastian, T Liu - Current medical science, 2021 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …

Association of psychiatric disorders with mortality among patients with COVID-19

K Nemani, C Li, M Olfson, EM Blessing… - JAMA …, 2021 - jamanetwork.com
Importance To date, the association of psychiatric diagnoses with mortality in patients
infected with coronavirus disease 2019 (COVID-19) has not been evaluated. Objective To …

Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind …

FC Zhu, XH Guan, YH Li, JY Huang, T Jiang, LH Hou… - The Lancet, 2020 - thelancet.com
Background This is the first randomised controlled trial for assessment of the
immunogenicity and safety of a candidate non-replicating adenovirus type-5 (Ad5)-vectored …

COVID-19-associated coagulopathy and disseminated intravascular coagulation

H Asakura, H Ogawa - International journal of hematology, 2021 - Springer
The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression
of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms. The …

Chest CT in COVID-19: what the radiologist needs to know

TC Kwee, RM Kwee - Radiographics, 2020 - pubs.rsna.org
Chest CT has a potential role in the diagnosis, detection of complications, and
prognostication of coronavirus disease 2019 (COVID-19). Implementation of appropriate …