Individuals with obesity and COVID‐19: a global perspective on the epidemiology and biological relationships

BM Popkin, S Du, WD Green, MA Beck… - Obesity …, 2020 - Wiley Online Library
The linkage of individuals with obesity and COVID‐19 is controversial and lacks systematic
reviews. After a systematic search of the Chinese and English language literature on COVID …

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

D Mathew, JR Giles, AE Baxter, DA Oldridge… - Science, 2020 - science.org
INTRODUCTION Many patients with coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

[HTML][HTML] The spatial landscape of lung pathology during COVID-19 progression

AF Rendeiro, H Ravichandran, Y Bram, V Chandar… - Nature, 2021 - nature.com
Recent studies have provided insights into the pathology of and immune response to COVID-
19,,,,,,–. However, a thorough investigation of the interplay between infected cells and the …

[HTML][HTML] Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li… - Gut, 2021 - gut.bmj.com
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence
suggesting that the GI tract is involved in this disease. We investigated whether the gut …

Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …

Lessons from the host defences of bats, a unique viral reservoir

AT Irving, M Ahn, G Goh, DE Anderson, LF Wang - Nature, 2021 - nature.com
There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

[HTML][HTML] Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis

AC Codo, GG Davanzo, L de Brito Monteiro… - Cell metabolism, 2020 - cell.com
COVID-19 can result in severe lung injury. It remained to be determined why diabetic
individuals with uncontrolled glucose levels are more prone to develop the severe form of …

Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …