[HTML][HTML] Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19

JH Ahn, JM Kim, SP Hong, SY Choi… - The Journal of …, 2021 - Am Soc Clin Investig
The upper respiratory tract is compromised in the early period of COVID-19, but SARS-CoV-
2 tropism at the cellular level is not fully defined. Unlike recent single-cell RNA-Seq analyses …

[HTML][HTML] Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium

F Jacob, SR Pather, WK Huang, F Zhang, SZH Wong… - Cell stem cell, 2020 - cell.com
Neurological complications are common in patients with COVID-19. Although severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …

[HTML][HTML] The microbial coinfection in COVID-19

X Chen, B Liao, L Cheng, X Peng, X Xu, Y Li… - Applied microbiology …, 2020 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel β-coronavirus,
is the main pathogenic agent of the rapidly spreading pneumonia called coronavirus …

Vitamin D status in hospitalized patients with SARS-CoV-2 infection

JL Hernández, D Nan… - The Journal of …, 2021 - academic.oup.com
Background The role of vitamin D status in COVID-19 patients is a matter of debate.
Objectives To assess serum 25-hydroxyvitamin D (25OHD) levels in hospitalized patients …

[HTML][HTML] The molecular virology of coronaviruses

E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - ASBMB
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …

[HTML][HTML] In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19

XJ Zhang, JJ Qin, X Cheng, L Shen, YC Zhao, Y Yuan… - Cell metabolism, 2020 - cell.com
Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …

DNA vaccines against COVID-19: Perspectives and challenges

MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus known
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …

Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review

E Ortiz-Prado, K Simbaña-Rivera… - … and infectious disease, 2020 - Elsevier
Coronaviruses are an extensive family of viruses that can cause disease in both animals
and humans. The current classification of coronaviruses recognizes 39 species in 27 …

[HTML][HTML] The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

TP Buzhdygan, BJ DeOre, A Baldwin-Leclair… - Neurobiology of …, 2020 - Elsevier
As researchers across the globe have focused their attention on understanding SARS-CoV-
2, the picture that is emerging is that of a virus that has serious effects on the vasculature in …

[HTML][HTML] SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …