The expanded lifespan of people, while a positive advance, has also amplified the
prevalence of age-related disorders, which include mild cognitive impairment, dementia …

Alzheimer's disease (AD) affects tens of millions of people worldwide. Despite the advances
in understanding the disease, there is an increased urgency for pharmacological …

Cancer-related cognitive impairment (CRCI) is a significant problem for patients receiving
chemotherapy. While a growing amount of pre-clinical and clinical evidence suggests that …

With the lack of success and increasing urgency for therapies capable of impacting
Alzheimer's disease (AD) and its progression, there are increasing efforts to expand testing …

Aging is considered the main risk factor for many chronic diseases that frequently appear at
advanced ages. However, the inevitability of this process is being questioned by recent …

While aging is the greatest risk factor for the development of neurodegenerative disease, the
role of aging in these diseases is poorly understood. In the inherited forms of these …

Alzheimer's disease (AD) is an age-associated neurodegenerative disease. As the
population ages, the increasing prevalence of AD threatens massive healthcare costs in the …

Despite the great body of research done on Alzheimer's disease, the underlying
mechanisms have not been vividly investigated. To date, the accumulation of amyloid‐beta …

The brain is endowed with a unique cellular composition and organization, embedded
within a vascular network and isolated from the circulating blood by a specialized frontier …

Background With population aging, the incidence of aging-related Alzheimer's disease (AD)
is increasing, accompanied by decreased autophagy activity. At present, Caenorhabditis …